Dilution Information
Rabbit anti-Human TdT Polyclonal Antibody | anti-TdT antibody
TdT
Reactivity
Human
Synonyms
TdT; Polyclonal Antibody; anti-TdT antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Form/Format
Anti-TdT is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
TdT Positive Lymphoma, Thymus
Localization
Nuclear
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8 degree C in the dark.
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Related Product Information for anti-TdT antibody
Terminal Deoxynucleotidyl Transferase (also known as TdT and terminal transferase) is a specialized DNA polymerase expressed in immature, pre-B, pre-T lymphoid cells and acute Lymphoblastic Leukemia/ Lymphoma cells. TdT catalyzes the addition of nucleotides to the 3' terminus of a DNA molecule. Unlike most DNA polymerases, it does not require a template. The preferred substrate of this enzyme is a protruding 3' overhang, but it can also add nucleotides to blunt or recessed 3' ends. TdT is normally found in cortical thymocytes and primitive lymphocytes. TdT antibody detects its antigen found in the nucleus of normal hematopoietic cells, normal cortical thymocytes and in the cytoplasm of megakaryocytes of the bone marrow. TdT expression is seen in over 90% of Acute Lymphocytic Leukemia cases with the exception of pre-B-Cell ALL, and normal mature T- or B-lymphocytes. TdT is positive for approximately one third of all cases of Chronic Myeloid Leukemia, making it a good indicator of better response to chemotherapy.
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Product Notes
The TdT (Catalog #AAA373040) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TdT reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "TdT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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