Rabbit TCHHL1 Polyclonal Antibody | anti-TCHHL1 antibody

TCHHL1, NT (S100A1, S-100, S100 calcium-binding protein A1)

Cat. Num. AAA645284

• Gene Names: TCHHL1; THHL1; S100A17
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity Purified; Purified by immunoaffinity chromatography
• Synonyms: TCHHL1; Polyclonal Antibody; NT (S100A1; S-100; S100 calcium-binding protein A1); Anti -TCHHL1; anti-TCHHL1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human S100A1/S100. Species Crossreactivity: Mouse, rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography
• Form/Format: Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.

• Applicable Applications for anti-TCHHL1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry.; Dilution: Immunofluorescence: 1:100-1:500; ELISA: 1:20,000; Western Blot: 1:500-1:1000; Immunohistochemistry (Paraffin): 10ug/ml
• Immunogen: Synthetic peptide corresponding to human S100A1/S100 at N-Terminal.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of extracts from A549 cells, using S100 A1. The lane on the right is treated with the synthesized peptide.)

Immunofluorescence (IF)

(Immunofluorescence analysis of A549 cells, using S100 A1.The picture on the right is treated with the synthesized peptide.)

Related Product Information for anti-TCHHL1 antibody

S100A1 has been suggested to be a regulator of myocardial contractility. S100A1 improves cardiac contractile performance both by regulating sarcoplasmic reticulum calcium ion handling and myofibrillar calcium ion responsiveness. S100 is an astrocyte marker.

Product Categories/Family for anti-TCHHL1 antibody

Antibodies; Abs to Calcium Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 56606114
• NCBI GeneID: 126637
• NCBI Accession #: NP_001008536.1
• NCBI GenBank Nucleotide #: NM_001008536.1
• UniProt Accession #: Q5QJ38; Q5VTJ9; B2RPK8
• Molecular Weight: 99,275 Da
• NCBI Official Full Name: trichohyalin-like protein 1
• NCBI Official Synonym Full Names: trichohyalin-like 1
• NCBI Official Symbol: TCHHL1
• NCBI Official Synonym Symbols: THHL1; S100A17
• NCBI Protein Information: trichohyalin-like protein 1; basalin; S100 calcium binding protein A17; S100 calcium-binding protein A17; intermediate filament-associated protein
• UniProt Protein Name: Trichohyalin-like protein 1
• Protein Family: Trichohyalin-like protein
• UniProt Gene Name: TCHHL1
• UniProt Synonym Gene Names: S100A17; THHL1
• UniProt Entry Name: TCHL1_HUMAN

NCBI Description

This gene belongs to the S100 fused-type protein (SFTP) gene family, and is located in a cluster of SFTP genes on chromosome 1q21. Several members of this family have been implicated in the development of complex skin disorders. This gene is evolutionarily conserved; its expression appears to be hair-specific and spatially restricted within the distal inner root sheath of the hair follicle. It thus may have an important role in hair morphogenesis. [provided by RefSeq, Aug 2013]

Uniprot Description

TCHHL1: Belongs to the S-100 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 1q21.3