Western Blot (WB)
(Western Blot analysis in mouse cerebellum tissue lysates (35ug/lane) usingMBS6006244. This demonstrates that MBS6006244 detected the Tbk1 protein (arrow).)
Rabbit anti-Mouse Tbk1 Polyclonal Antibody | anti-Tbk1 antibody
Tbk1, NT (Tbk1, Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1) (APC)
Gene Names
Tbk1; AI462036; AW048562; 1200008B05Rik
Reactivity
Mouse
Applications
Western Blot
Purity
Purified by Protein A and Peptide Affinity Chromatography.
Synonyms
Tbk1; Polyclonal Antibody; NT (Tbk1; Serine/threonine-protein kinase TBK1; T2K; TANK-binding kinase 1) (APC); TANK-binding kinase 1; anti-Tbk1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse Tbk1.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-Tbk1 antibody
Western Blot (WB), FLISA
Application Notes
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 8-35 in the N-terminal region of mouse Tbk1.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot analysis in mouse cerebellum tissue lysates (35ug/lane) usingMBS6006244. This demonstrates that MBS6006244 detected the Tbk1 protein (arrow).)
Western Blot (WB)
(Western Blot analysis in mouse cerebellum tissue lysates (35ug/lane) usingMBS6006244. This demonstrates that MBS6006244 detected the Tbk1 protein (arrow).)
Related Product Information for anti-Tbk1 antibody
Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.
Product Categories/Family for anti-Tbk1 antibody
References
1. Parvatiyar, K., et al. J. Biol. Chem. 285(20):14999-15009(2010). 2. Watanabe, T., et al. J. Clin. Invest. 120(5):1645-1662(2010). 3. Gabhann, J.N., et al. J. Immunol. 184(5):2314-2320(2010). 4. Munoz, M.C., et al. J. Endocrinol. 201(2):185-197(2009). 5. Miyahira, A.K., et al. J. Immunol. 182(4):2248-2257(2009).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
83,425 Da
NCBI Official Full Name
serine/threonine-protein kinase TBK1
NCBI Official Synonym Full Names
TANK-binding kinase 1
NCBI Official Symbol
Tbk1
NCBI Official Synonym Symbols
AI462036; AW048562; 1200008B05Rik
NCBI Protein Information
serine/threonine-protein kinase TBK1; T2K; serine/threonine protein kinase TBK1
UniProt Protein Name
Serine/threonine-protein kinase TBK1
Protein Family
UniProt Gene Name
Tbk1
UniProt Entry Name
TBK1_MOUSE
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Product Notes
The Tbk1 tbk1 (Catalog #AAA6354074) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Tbk1, NT (Tbk1, Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1) (APC) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Tbk1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the Tbk1 tbk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tbk1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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