Western Blot (WB)
(Western Blot analysis of TBC1D20 expression in transfected 293T cell line by TBC1D20 polyclonal antibody. Lane1:TBC1D20 transfected lysate (44.33kD). Lane2:Non-transfected lysate.)
Mouse anti-Human TBC1D20 Polyclonal Antibody | anti-TBC1D20 antibody
TBC1D20 (TBC1 Domain Family, Member 20, C20orf140, FLJ45119)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of TBC1D20 expression in transfected 293T cell line by TBC1D20 polyclonal antibody. Lane1:TBC1D20 transfected lysate (44.33kD). Lane2:Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of TBC1D20 expression in transfected 293T cell line by TBC1D20 polyclonal antibody. Lane1:TBC1D20 transfected lysate (44.33kD). Lane2:Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replication. Depletion of this protein inhibits replication of the virus and HCV infection. Mutations in this gene are associated with Warburg micro syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Uniprot Description
TBC1D20: May act as a GTPase-activating protein for Rab family protein(s). 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; GAPs; GAPs, Rab; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: endoplasmic reticulum membrane; nuclear membrane; endoplasmic reticulum; integral to Golgi membrane
Molecular Function: protein binding; Rab GTPase binding
Biological Process: acrosome formation; ER to Golgi vesicle-mediated transport; virus assembly; positive regulation of viral protein levels in host cell; Golgi organization and biogenesis
Disease: Warburg Micro Syndrome 4
Research Articles on TBC1D20
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Product Notes
The TBC1D20 tbc1d20 (Catalog #AAA6009358) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TBC1D20 (TBC1 Domain Family, Member 20, C20orf140, FLJ45119) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TBC1D20 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the TBC1D20 tbc1d20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MALRSAQGDG PTSGHWDGGA EKADFNAKRK KKVAEIHQAL NSDPTDVAAL RRMAISEGGL LTDEIRRKVW PKLLNVNAND PPPISGKNLR QMSKDYQQVL LDVRRSLRRF PPGMPEEQRE GLQEELIDII LLILERNPQL HYYQGYHDIV VTFLLVVGER LATSLVEKLS THHLRDFMDP TMDNTKHILN YLMPIIDQVN PELHDFMQSA EVGTIFALSW LITWFGHVLS DFRHVVRLYD FFLAYHPLMP IYFAAVIVLY REQEVLDCDC DMASVHHLLS QIPQDLPYET LISRAGDLFV QFPPSELARE AAAQQQAERT AASTFKDFEL ASAQQRPDMV LRQRFRGLLR PEDRTKDVLT KPRTNRFVKL AVMGLTVALG AAALAVVKSA LEWAPKFQLQ LFP. It is sometimes possible for the material contained within the vial of "TBC1D20, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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