Western Blot (WB)
(Western blot analysis of TBC1D2 using COLO205 whole cell lysates)
Rabbit anti-Human TBC1D2 Polyclonal Antibody | anti-TBC1D2 antibody
TBC1D2 Antibody
Gene Names
TBC1D2; PARIS1; PARIS-1; TBC1D2A
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
TBC1D2; Polyclonal Antibody; TBC1D2 Antibody; PARIS 1; PARIS1; PP8997; Prostate antigen recognized and identified by SEREX; TBC1 domain family; member 2; TBC1D2A; anti-TBC1D2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
TBC1D2 antibody detects endogenous levels of total TBC1D2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
928
Applicable Applications for anti-TBC1D2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human TBC1D2
Subcellular Location
Cytoplasm. Cytoplasmic Vesicle. Cell Junction
Tissue Specificity
Expressed in a broad range of tissues, especially in kidney, liver, lung and placenta. Also expressed in keratinocytes and epithelia-containing organs. Isoform 2 is differentially expressed in prostate normal and cancer cells (at protein level).
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Similarity
Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (83%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of TBC1D2 using COLO205 whole cell lysates)
Western Blot (WB)
(Western blot analysis of TBC1D2 using COLO205 whole cell lysates)
Related Product Information for anti-TBC1D2 antibody
Function: Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
Subunit Structure: Interacts with activated RAC1 and CDH1.
Subunit Structure: Interacts with activated RAC1 and CDH1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 105 kDa
Predicted: 106 kDa
Predicted: 106 kDa
NCBI Official Full Name
TBC1 domain family member 2A isoform 1
NCBI Official Synonym Full Names
TBC1 domain family member 2
NCBI Official Symbol
TBC1D2
NCBI Official Synonym Symbols
PARIS1; PARIS-1; TBC1D2A
NCBI Protein Information
TBC1 domain family member 2A
UniProt Protein Name
TBC1 domain family member 2A
Protein Family
UniProt Gene Name
TBC1D2
UniProt Synonym Gene Names
PARIS1; PP8997; TBC1D2A; PARIS-1
Uniprot Description
Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
Research Articles on TBC1D2
Similar Products
Product Notes
The TBC1D2 tbc1d2 (Catalog #AAA9610273) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TBC1D2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TBC1D2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the TBC1D2 tbc1d2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TBC1D2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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