Western Blot (WB)
(Western blot analysis of TASK-1 using Jurkat whole cell lysates)
Rabbit TASK-1 Polyclonal Antibody | anti-TASK-1 antibody
TASK-1 Antibody
Gene Names
KCNK3; OAT1; PPH4; TASK; TBAK1; K2p3.1; TASK-1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
TASK-1; Polyclonal Antibody; TASK-1 Antibody; Acid sensitive potassium channel protein TASK 1; Acid sensitive potassium channel protein TASK; Acid-sensitive potassium channel protein TASK-1; Cardiac two pore background K(+) channel; cTBAK 1; K2p3.1; KCNK3; KCNK3_HUMAN; OAT1; Potassium channel subfamily K member 3; potassium channel; subfamily K; member 3; Potassium inwardly rectifying channel subfamily K member 3; PPH4; rTASK; TASK 1; TASK; TBAK1; TWIK related acid sensitive K+ channel; TWIK-related acid-sensitive K(+) channel 1; Two P domain potassium channel; Two pore K(+) channel KT3.; Two pore K(+) channel KT3.1; Two pore potassium channel KT3.1; anti-TASK-1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TASK-1 antibody detects endogenous levels of total TASK-1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
394
Applicable Applications for anti-TASK-1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human TASK-1
Subcellular Location
Membrane.
Tissue Specificity
Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Similarity
Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (87%), Dog (100%), Chicken (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of TASK-1 using Jurkat whole cell lysates)
Western Blot (WB)
(Western blot analysis of TASK-1 using Jurkat whole cell lysates)
Related Product Information for anti-TASK-1 antibody
Function: pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.
Subunit Structure: Homodimer (Probable). Heterodimer with KCNK1.
Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Subunit Structure: Homodimer (Probable). Heterodimer with KCNK1.
Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 43 kDa
Predicted: 44 kDa
Predicted: 44 kDa
NCBI Official Full Name
potassium channel subfamily K member 3
NCBI Official Synonym Full Names
potassium two pore domain channel subfamily K member 3
NCBI Official Symbol
KCNK3
NCBI Official Synonym Symbols
OAT1; PPH4; TASK; TBAK1; K2p3.1; TASK-1
NCBI Protein Information
potassium channel subfamily K member 3
UniProt Protein Name
Potassium channel subfamily K member 3
UniProt Gene Name
KCNK3
UniProt Synonym Gene Names
TASK; TASK1; Two pore K(+) channel KT3.1
NCBI Description
This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008]
Uniprot Description
pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.
Research Articles on TASK-1
Similar Products
Product Notes
The TASK-1 kcnk3 (Catalog #AAA9608937) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TASK-1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TASK-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the TASK-1 kcnk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TASK-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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