Rabbit anti-Human TAS1R2 Polyclonal Antibody | anti-TAS1R2 antibody

TAS1R2, CT (TAS1R2, GPR71, T1R2, TR2, Taste receptor type 1 member 2, G-protein coupled receptor 71, Sweet taste receptor T1R2) (MaxLight 490)

Cat. Num. AAA6353639

• Gene Names: TAS1R2; TR2; T1R2; GPR71
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: TAS1R2; Polyclonal Antibody; CT (TAS1R2; GPR71; T1R2; TR2; Taste receptor type 1 member 2; G-protein coupled receptor 71; Sweet taste receptor T1R2) (MaxLight 490); Sweet taste receptor T1R2; anti-TAS1R2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human TAS1R2 at ~95kD.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

• Applicable Applications for anti-TAS1R2 antibody: Western Blot (WB), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 691-718 in the C-terminal region of human TAS1R2. UniProt Accession: Q8TE23. Cellular Localization: Cell membrane; Multi-pass membrane protein
• Conjugate: MaxLight490
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of MBS643481 in K562 cell line lysates (35ug/lane). This demonstrates that MBS643481 detected the TAS1R2 protein (arrow).)

Related Product Information for anti-TAS1R2 antibody

Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.

Product Categories/Family for anti-TAS1R2 antibody

Antibodies; G Protein Receptors

References

1. Wendell, S., et al. J. Dent. Res. 89(11):1198-1202(2010). 2. Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010). 3. Assadi-Porter, F.M., et al. J. Mol. Biol. 398(4):584-599(2010). 4. Chandrashekar, J., et al. Nature 444(7117):288-294(2006). 5. Galindo-Cuspinera, V., et al. Nature 441(7091):354-357(2006).

NCBI and Uniprot Product Information

• NCBI GI #: 112789566
• NCBI GeneID: 80834
• NCBI Accession #: NP_689418.2
• NCBI GenBank Nucleotide #: NM_152232.2
• UniProt Accession #: Q8TE23; Q5TZ19
• Molecular Weight: 95,183 Da
• NCBI Official Full Name: taste receptor type 1 member 2
• NCBI Official Synonym Full Names: taste receptor, type 1, member 2
• NCBI Official Symbol: TAS1R2
• NCBI Official Synonym Symbols: TR2; T1R2; GPR71
• NCBI Protein Information: taste receptor type 1 member 2; sweet taste receptor T1R2; G protein-coupled receptor 71; G-protein coupled receptor 71
• UniProt Protein Name: Taste receptor type 1 member 2
• Protein Family: Taste receptor
• UniProt Gene Name: TAS1R2
• UniProt Synonym Gene Names: GPR71; T1R2; TR2
• UniProt Entry Name: TS1R2_HUMAN

Uniprot Description

TAS1R2: Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.

Protein type: Membrane protein, integral; GPCR, family 3; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: plasma membrane; integral to membrane; receptor complex

Molecular Function: protein heterodimerization activity; sweet taste receptor activity; taste receptor activity

Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; sensory perception of sweet taste; detection of chemical stimulus involved in sensory perception of sweet taste