Rabbit TALDO1 Polyclonal Antibody | anti-TALDO1 antibody

TALDO1 antibody

Cat. Num. AAA9408104

• Gene Names: TALDO1; TAL; TALH; TAL-H; TALDOR
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunofluorescence
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: TALDO1; Polyclonal Antibody; TALDO1 antibody; TAL; TALH; TAL-H; TALDOR; anti-TALDO1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total TALDO1 antibody.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 337

• Applicable Applications for anti-TALDO1 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500 - 1:2000; Immunofluorescence: 1:50 - 1:200
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human TALDO1.
• Target Name: TALDO1
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using TALDO1 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of HeLa cell using TALDO1 antibody. Blue: DAPI for nuclear staining.)

Related Product Information for anti-TALDO1 antibody

Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.

Product Categories/Family for anti-TALDO1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 5803187
• NCBI GeneID: 6888
• NCBI Accession #: NP_006746.1
• NCBI GenBank Nucleotide #: NM_006755.1
• UniProt Accession #: P37837; O00751; Q8WV32; Q8WZ45; B2R8M2
• Molecular Weight: 37,540 Da
• NCBI Official Full Name: transaldolase
• NCBI Official Synonym Full Names: transaldolase 1
• NCBI Official Symbol: TALDO1
• NCBI Official Synonym Symbols: TAL; TALH; TAL-H; TALDOR
• NCBI Protein Information: transaldolase
• UniProt Protein Name: Transaldolase
• Protein Family: Transaldolase
• UniProt Gene Name: TALDO1
• UniProt Synonym Gene Names: TAL; TALDO; TALDOR
• UniProt Entry Name: TALDO_HUMAN

NCBI Description

Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]

Uniprot Description

TALDO1: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency). It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Belongs to the transaldolase family. Type 1 subfamily.

Protein type: EC 2.2.1.2; Carbohydrate Metabolism - pentose phosphate pathway; Transferase

Chromosomal Location of Human Ortholog: 11p15.5-p15.4

Cellular Component: cytoplasm; nucleus; cytosol

Molecular Function: transaldolase activity

Biological Process: pentose-phosphate shunt; carbohydrate metabolic process; energy reserve metabolic process; pathogenesis; xylulose biosynthetic process

Disease: Transaldolase Deficiency