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Western Blot (WB) (Western BlotPositive WB detected in: Zebrafish tissue 20ug, 10ugAll lanes: tal1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 36, 23 KDaObserved band size: 36 KDa)

Rabbit anti-Zebrafish tal1 Polyclonal Antibody | anti-tal1 antibody

tal1 Antibody

Gene Names
tal1; scl; tal-1; SCL-beta; scl/tal1; SCL-alpha; zgc:85605
Reactivity
Zebrafish
Applications
ELISA, Western Blot
Purity
>95%, Protein G purified
Synonyms
tal1; Polyclonal Antibody; tal1 Antibody; T-cell acute lymphocytic leukemia protein 1 homolog; TAL-1; Stem cell protein; zSCL; anti-tal1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Zebrafish
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
324
Applicable Applications for anti-tal1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:5000
Immunogen
Recombinant Zebrafish T-cell acute lymphocytic leukemia protein 1 homolog protein (1-324AA)
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: Zebrafish tissue 20ug, 10ugAll lanes: tal1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 36, 23 KDaObserved band size: 36 KDa)

Western Blot (WB) (Western BlotPositive WB detected in: Zebrafish tissue 20ug, 10ugAll lanes: tal1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 36, 23 KDaObserved band size: 36 KDa)
Related Product Information for anti-tal1 antibody
Transcription factor that plays a pivotal role in hemopoietic and endothelial development, acting synergistically with lmo2 and downstream of clo. Specifies mesodermal precursors to a hemangioblast cell fate. Hemangioblasts are bipotential precursors of blood and endothelium, and in the absence of hemopoietic induction cues such as gata1, tal1/scl-lmo2-induced hemangioblasts differentiate into endothelial cells. Isoform alpha and isoform beta are redundant for the initiation of primitive hemopoiesis but have distinct roles in the regulation of primitive erythroid differentiation and definitive hemopoietic stem cell specification, most likely due to differences in expression levels. Specification of definitive hemopoietic stem cells requires isoform beta. DNA binding is required for erythroid maturation, but not for its other hemopoietic functions. Endothelial roles include development of the dorsal aorta, the site of definitive hemopoiesis in the embryo. Required for angiogenesis but not angioblast specification. Has an additional role in endocardium formation during heart development. May play a role in central nervous system development.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,925 Da
NCBI Official Full Name
T-cell acute lymphocytic leukemia protein 1 homolog
NCBI Official Synonym Full Names
T-cell acute lymphocytic leukemia 1
NCBI Official Symbol
tal1
NCBI Official Synonym Symbols
scl; tal-1; SCL-beta; scl/tal1; SCL-alpha; zgc:85605
NCBI Protein Information
T-cell acute lymphocytic leukemia protein 1 homolog
UniProt Protein Name
T-cell acute lymphocytic leukemia protein 1 homolog
Protein Family
UniProt Gene Name
tal1
UniProt Synonym Gene Names
TAL-1; zSCL

Uniprot Description

Transcription factor that plays a pivotal role in hemopoietic and endothelial development, acting synergistically with lmo2 and downstream of clo. Specifies mesodermal precursors to a hemangioblast cell fate. Hemangioblasts are bipotential precursors of blood and endothelium, and in the absence of hemopoietic induction cues such as gata1, tal1/scl-lmo2-induced hemangioblasts differentiate into endothelial cells. Isoform alpha and isoform beta are redundant for the initiation of primitive hemopoiesis but have distinct roles in the regulation of primitive erythroid differentiation and definitive hemopoietic stem cell specification, most likely due to differences in expression levels. Specification of definitive hemopoietic stem cells requires isoform beta. DNA binding is required for erythroid maturation, but not for its other hemopoietic functions. Endothelial roles include development of the dorsal aorta, the site of definitive hemopoiesis in the embryo. Required for angiogenesis but not angioblast specification. Has an additional role in endocardium formation during heart development. May play a role in central nervous system development.

Research Articles on tal1

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Product Notes

The tal1 tal1 (Catalog #AAA7103893) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The tal1 Antibody reacts with Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's tal1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:5000. Researchers should empirically determine the suitability of the tal1 tal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "tal1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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