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Western Blot (WB) (Anti-(Mouse) Tal1 Antibody (Center) at 1:2000 dilution + K562 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 34 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human Tal1 Polyclonal Antibody | anti-Tal1 antibody

(Mouse) Tal1 Antibody (Center)

Gene Names
Tal1; Scl; tal-1; bHLHa17; SCL/tal-1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Tal1; Polyclonal Antibody; (Mouse) Tal1 Antibody (Center); T-cell acute lymphocytic leukemia protein 1 homolog; TAL-1; Stem cell protein; Scl; Tal-1; anti-Tal1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This mouse Tal1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 154-188 amino acids from the Central region of mouse Tal1.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Length
329
Applicable Applications for anti-Tal1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-(Mouse) Tal1 Antibody (Center) at 1:2000 dilution + K562 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 34 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-(Mouse) Tal1 Antibody (Center) at 1:2000 dilution + K562 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 34 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB)

(Anti-(Mouse) Tal1 Antibody (Center) at 1:1000 dilution + mouse spleen lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 34kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-(Mouse) Tal1 Antibody (Center) at 1:1000 dilution + mouse spleen lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 34kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-Tal1 antibody
Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.
Product Categories/Family for anti-Tal1 antibody
References
Begley C.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:869-873(1991).
Visvader J.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:13707-13712(1997).
Tang T.,et al.J. Biol. Chem. 277:18365-18372(2002).
Goardon N.,et al.EMBO J. 25:357-366(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34279
NCBI Official Full Name
T-cell acute lymphocytic leukemia protein 1 homolog
NCBI Official Synonym Full Names
T cell acute lymphocytic leukemia 1
NCBI Official Symbol
Tal1
NCBI Official Synonym Symbols
Scl; tal-1; bHLHa17; SCL/tal-1
NCBI Protein Information
T-cell acute lymphocytic leukemia protein 1 homolog
UniProt Protein Name
T-cell acute lymphocytic leukemia protein 1 homolog
Protein Family
UniProt Gene Name
Tal1
UniProt Synonym Gene Names
Scl; Tal-1; TAL-1
UniProt Entry Name
TAL1_MOUSE

Uniprot Description

TAL1: a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

Protein type: DNA-binding; Transcription factor; Oncoprotein

Cellular Component: transcription factor complex; protein complex; histone deacetylase complex; nuclear chromatin; nucleus

Molecular Function: protein dimerization activity; protein binding; enzyme binding; DNA binding; protein heterodimerization activity; histone deacetylase binding; chromatin binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; positive regulation of chromatin assembly or disassembly; erythrocyte maturation; megakaryocyte differentiation; astrocyte fate commitment; multicellular organismal development; positive regulation of transcription, DNA-dependent; locomotory behavior; negative regulation of transcription from RNA polymerase II promoter; positive regulation of mitotic cell cycle; neuron differentiation; regulation of transcription, DNA-dependent; erythrocyte differentiation; hemopoiesis; angiogenesis; cell differentiation; regulation of myeloid cell differentiation; cell fate commitment; transcription, DNA-dependent; embryonic hemopoiesis; positive regulation of erythrocyte differentiation; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; positive regulation of protein complex assembly; generation of neurons; positive regulation of cell division; spinal cord association neuron differentiation; myeloid cell differentiation; positive regulation of transcription from RNA polymerase II promoter; platelet formation

Research Articles on Tal1

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Product Notes

The Tal1 tal1 (Catalog #AAA9203148) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The (Mouse) Tal1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Tal1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Tal1 tal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tal1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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