Rabbit anti-Human TAGAP Polyclonal Antibody | anti-TAGAP antibody

TAGAP Rabbit pAb

Cat. Num. AAA4758178

• Gene Names: TAGAP; FKSG15; IDDM21; TAGAP1; ARHGAP47
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity purified
• Synonyms: TAGAP; Polyclonal Antibody; TAGAP Rabbit pAb; FKSG15; IDDM21; TAGAP1; ARHGAP47; anti-TAGAP antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: -20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-TAGAP antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Full length fusion protein
• Conjugation: Unconjugated
• Molecular Function: This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms.
• Modification: Unmodified
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-3: A549, Jurkat and HEPG2 cell lysates, Primary antibody: 824808(TAGAP Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)

Product Categories/Family for anti-TAGAP antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 16198399
• NCBI GeneID: 117289
• UniProt Accession #: Q8N103; Q2NKM8; Q8NI40; Q96KZ2; Q96QA2
• Molecular Weight: 29,977 Da
• NCBI Official Full Name: Homo sapiens T-cell activation RhoGTPase activating protein, mRNA
• NCBI Official Synonym Full Names: T-cell activation RhoGTPase activating protein
• NCBI Official Symbol: TAGAP
• NCBI Official Synonym Symbols: FKSG15; IDDM21; TAGAP1; ARHGAP47
• NCBI Protein Information: T-cell activation Rho GTPase-activating protein
• UniProt Protein Name: T-cell activation Rho GTPase-activating protein
• Protein Family: T-cell activation Rho GTPase-activating protein
• UniProt Gene Name: TAGAP
• UniProt Synonym Gene Names: TAGAP1
• UniProt Entry Name: TAGAP_HUMAN

NCBI Description

This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]

Uniprot Description

TAGAP: an apparent GTPase-activating protein (GAP) for Rho monomeric G proteins. May play important roles during T-cell activation. Mutations have been associated with various autoimmune conditions including rheumatoid arthritis, Crohn¿s disease, and celiac disease. Four isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 6q25.3

Cellular Component: cytosol

Molecular Function: guanyl-nucleotide exchange factor activity

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity