Rabbit TAF7 Polyclonal Antibody | anti-TAF7 antibody

TAF7 Rabbit Polyclonal

Cat. Num. AAA7604721

• Gene Names: TAF7; TAF2F; TAFII55
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: TAF7; Polyclonal Antibody; TAF7 Rabbit Polyclonal; anti-TAF7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 349

• Applicable Applications for anti-TAF7 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
• Immunogen: TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human cervical cancer using MBS7604721 (TAF7 antibody) at dilution of 1:100)

Western Blot (WB)

(Jurkat cells were subjected to SDS PAGE followed by western blot with MBS7604721 (TAF7 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 119582370
• NCBI GeneID: 6879
• Molecular Weight: 40,259 Da
• NCBI Official Full Name: TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
• NCBI Official Synonym Full Names: TATA-box binding protein associated factor 7
• NCBI Official Symbol: TAF7
• NCBI Official Synonym Symbols: TAF2F; TAFII55
• NCBI Protein Information: transcription initiation factor TFIID subunit 7
• UniProt Protein Name: Transcription initiation factor TFIID subunit 7
• Protein Family: Transcription initiation factor
• UniProt Gene Name: TAF7
• UniProt Synonym Gene Names: TAF2F; TAFII55; TAF(II)55; TAFII-55; TAFII55
• UniProt Entry Name: TAF7_HUMAN

NCBI Description

The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. [provided by RefSeq, Jul 2008]

Uniprot Description

TAF7: Functions as a component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively). Belongs to the TAF7 family.

Protein type: DNA-binding; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: Golgi apparatus; nucleoplasm; transcription elongation factor complex b; transcription factor TFIID complex

Molecular Function: histone acetyltransferase binding; protein binding; thyroid hormone receptor binding; transcription coactivator activity; transcription factor activity; transcription factor binding; vitamin D receptor binding

Biological Process: estrogen receptor signaling pathway; negative regulation of histone acetylation; negative regulation of protein kinase activity; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; spermine transport; transcription from RNA polymerase II promoter; transcription initiation; transcription initiation from RNA polymerase II promoter; transcriptional preinitiation complex assembly