Western Blot (WB)
(TAF4B Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TAF4B antibody detected the TAF4B protein (arrow).)
Rabbit TAF4B Polyclonal Antibody | anti-TAF4B antibody
TAF4B Antibody (C-term)
Western Blot (WB)
(TAF4B Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TAF4B antibody detected the TAF4B protein (arrow).)
Western Blot (WB)
(TAF4B Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TAF4B antibody detected the TAF4B protein (arrow).)
Flow Cytometry (FC/FACS)
(TAF4B Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(TAF4B Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
participate, with TATA binding protein (TBP; MIM 600075), in the
formation of the TFIID protein complex (see MIM 313650), which is
involved in the initiation of gene transcription by RNA polymerase
II (see MIM 180660).
Gazit, K., et al. J. Biol. Chem. 284(39):26286-26296(2009)
Knauff, E.A., et al. Hum. Reprod. 24(9):2372-2378(2009)
Teye, K., et al. Int. J. Oncol. 33(6):1271-1280(2008)
Liu, W.L., et al. Mol. Cell 29(1):81-91(2008)
NCBI and Uniprot Product Information
NCBI Description
TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific TAF that may be responsible for mediating transcription by a subset of activators in B cells. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Uniprot Description
TAF4B: Cell type-specific subunit of TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAFII105 is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Belongs to the TAF4 family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 18q11.2
Cellular Component: nucleoplasm; transcription factor TFIID complex; cytoplasm; nucleolus
Molecular Function: NF-kappaB binding; DNA binding; protein heterodimerization activity; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; oogenesis; transcription initiation from RNA polymerase II promoter; viral reproduction; regulation of transcription, DNA-dependent; RNA elongation from RNA polymerase II promoter; spermatogenesis; gene expression
Disease: Spermatogenic Failure 13
Research Articles on TAF4B
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Product Notes
The TAF4B taf4b (Catalog #AAA9206414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 647-675. The TAF4B Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's TAF4B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the TAF4B taf4b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAF4B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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