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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer using MBS7604701 (TACC2 antibody) at dilution of 1:100)

Rabbit TACC2 Polyclonal Antibody | anti-TACC2 antibody

TACC2 Rabbit Polyclonal

Gene Names
TACC2; AZU-1; ECTACC
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
TACC2; Polyclonal Antibody; TACC2 Rabbit Polyclonal; anti-TACC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
2875
Applicable Applications for anti-TACC2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Immunogen
Transforming, acidic coiled-coil containing protein 2
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7604701 (TACC2 antibody) at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer using MBS7604701 (TACC2 antibody) at dilution of 1:100)

Western Blot (WB)

(mouse testis tissue were subjected to SDS PAGE followed by western blot with MBS7604701 (TACC2 antibody) at dilution of 1:500)

Western Blot (WB) (mouse testis tissue were subjected to SDS PAGE followed by western blot with MBS7604701 (TACC2 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
108,690 Da
NCBI Official Full Name
transforming acidic coiled-coil-containing protein 2 isoform f
NCBI Official Synonym Full Names
transforming acidic coiled-coil containing protein 2
NCBI Official Symbol
TACC2
NCBI Official Synonym Symbols
AZU-1; ECTACC
NCBI Protein Information
transforming acidic coiled-coil-containing protein 2
UniProt Protein Name
Transforming acidic coiled-coil-containing protein 2
UniProt Gene Name
TACC2
UniProt Synonym Gene Names
AZU-1
UniProt Entry Name
TACC2_HUMAN

NCBI Description

Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

TACC2: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker. Belongs to the TACC family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 10q26

Cellular Component: cytoplasm; microtubule cytoskeleton; microtubule organizing center; nucleolus; nucleus

Molecular Function: nuclear hormone receptor binding

Biological Process: cell proliferation; cerebral cortex development; microtubule cytoskeleton organization and biogenesis

Research Articles on TACC2

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Product Notes

The TACC2 tacc2 (Catalog #AAA7604701) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TACC2 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TACC2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the TACC2 tacc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TACC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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