Western Blot (WB)
(Western blot analysis of TACC1 expression in mouse testis extract (lane 1) and U87 whole cell lysates (lane 2). TACC1 at 100KD was detected using rabbit anti- TACC1 Antigen Affinity purified polyclonal antibody at 0.5ug/mL. The blot was developed using chemiluminescence (ECL) method. )
Rabbit anti-Human, Mouse TACC1 Polyclonal Antibody | anti-TACC1 antibody
Anti-TACC1 Antibody
Gene Names
TACC1; Ga55
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
TACC1; Polyclonal Antibody; Anti-TACC1 Antibody; Ga 55; Ga55; TACC 1; Tacc1; Taxin 1; Taxin-1; Taxin1; O75410; Transforming acidic coiled-coil-containing protein 1; transforming acidic coiled-coil containing protein 1; anti-TACC1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
395
Applicable Applications for anti-TACC1 antibody
Western Blot (WB)
Application Notes
Western Blot: 0.1-0.5ug/ml
Notes
Tested Species: In-house tested species with positive results.
Other applications have not been tested.
Other applications have not been tested.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human TACC1 (196-235aa MTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKP), different from the related mouse sequence by fourteen amino acids.
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Western Blot (WB)
(Western blot analysis of TACC1 expression in mouse testis extract (lane 1) and U87 whole cell lysates (lane 2). TACC1 at 100KD was detected using rabbit anti- TACC1 Antigen Affinity purified polyclonal antibody at 0.5ug/mL. The blot was developed using chemiluminescence (ECL) method. )
Western Blot (WB)
(Western blot analysis of TACC1 expression in mouse testis extract (lane 1) and U87 whole cell lysates (lane 2). TACC1 at 100KD was detected using rabbit anti- TACC1 Antigen Affinity purified polyclonal antibody at 0.5ug/mL. The blot was developed using chemiluminescence (ECL) method. )
Related Product Information for anti-TACC1 antibody
Rabbit IgG polyclonal antibody for Transforming acidic coiled-coil-containing protein 1(TACC1) detection.
Background: Transforming acidic coiled-coil-containing protein 1 is a protein that in humans is encoded by the TACC1 gene. This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene.
Background: Transforming acidic coiled-coil-containing protein 1 is a protein that in humans is encoded by the TACC1 gene. This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene.
References
1. Delaval B, Ferrand A, Conte N, Larroque C, Hernandez-Verdun D, Prigent C, Birnbaum D (Jun 2004). "Aurora B -TACC1 protein complex in cytokinesis".Oncogene. 23 (26): 4516-22.
2. Conte N, Delaval B, Ginestier C, Ferrand A, Isnardon D, Larroque C, Prigent C, Séraphin B, Jacquemier J, Birnbaum D (Nov 2003). "TACC1-chTOG-Aurora A protein complex in breast cancer". Oncogene. 22 (50): 8102-16.
2. Conte N, Delaval B, Ginestier C, Ferrand A, Isnardon D, Larroque C, Prigent C, Séraphin B, Jacquemier J, Birnbaum D (Nov 2003). "TACC1-chTOG-Aurora A protein complex in breast cancer". Oncogene. 22 (50): 8102-16.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17,815 Da
NCBI Official Full Name
transforming acidic coiled-coil-containing protein 1 isoform 2
NCBI Official Synonym Full Names
transforming acidic coiled-coil containing protein 1
NCBI Official Symbol
TACC1
NCBI Official Synonym Symbols
Ga55
NCBI Protein Information
transforming acidic coiled-coil-containing protein 1
UniProt Protein Name
Transforming acidic coiled-coil-containing protein 1
Protein Family
UniProt Gene Name
TACC1
UniProt Synonym Gene Names
KIAA1103
NCBI Description
This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
Uniprot Description
TACC1: Likely involved in the processes that promote cell division prior to the formation of differentiated tissues. Belongs to the TACC family. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell development/differentiation; Cytoskeletal
Chromosomal Location of Human Ortholog: 8p11.22
Cellular Component: cytoplasm; intermediate filament cytoskeleton; microtubule cytoskeleton
Molecular Function: protein binding
Biological Process: cell proliferation; cerebral cortex development; microtubule cytoskeleton organization and biogenesis
Research Articles on TACC1
Similar Products
Product Notes
The TACC1 tacc1 (Catalog #AAA178687) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TACC1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TACC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the TACC1 tacc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TACC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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