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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MBS7124041(TAC1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))

Rabbit TAC1 Polyclonal Antibody | anti-TAC1 antibody

TAC1 Antibody

Gene Names
TAC1; NK2; NPK; NKNA; TAC2; Hs.2563
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
TAC1; Polyclonal Antibody; TAC1 Antibody; tachykinin; precursor 1; anti-TAC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-TAC1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:5000
IHC: 1:25-1:100
Immunogen
Fusion protein of human TAC1
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MBS7124041(TAC1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MBS7124041(TAC1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7124041(TAC1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7124041(TAC1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))
Product Categories/Family for anti-TAC1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
129
NCBI Official Full Name
Protachykinin-1
NCBI Official Synonym Full Names
tachykinin, precursor 1
NCBI Official Symbol
TAC1
NCBI Official Synonym Symbols
NK2; NPK; NKNA; TAC2; Hs.2563
NCBI Protein Information
protachykinin-1; PPT; substance K; substance P; neurokinin 1; neurokinin 2; neurokinin A; neuromedin L; tachykinin 2; neuropeptide K; neurokinin alpha; preprotachykinin; neuropeptide gamma; tachykinin, precursor 1 (substance K, substance P, neurokinin 1,
UniProt Protein Name
Protachykinin-1
Protein Family
UniProt Gene Name
TAC1
UniProt Synonym Gene Names
NKA; NKNA; TAC2; NKA; NPK
UniProt Entry Name
TKN1_HUMAN

NCBI Description

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Uniprot Description

TAC1: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: extracellular space; cell soma; axon; extracellular region; plasma membrane

Molecular Function: protein binding; substance P receptor binding

Biological Process: tachykinin signaling pathway; negative regulation of heart rate; insemination; response to hormone stimulus; response to morphine; response to lipopolysaccharide; response to pain; sensory perception of pain; positive regulation of saliva secretion; synaptic transmission; elevation of cytosolic calcium ion concentration; cell-cell signaling; positive regulation of acute inflammatory response; positive regulation of lymphocyte proliferation; neuropeptide signaling pathway; regulation of blood pressure; positive regulation of stress fiber formation; positive regulation of action potential; inflammatory response; associative learning; detection of abiotic stimulus; positive regulation of synaptic transmission, cholinergic; positive regulation of synaptic transmission, GABAergic; positive regulation of ossification; long-term memory

Research Articles on TAC1

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Product Notes

The TAC1 tac1 (Catalog #AAA7124041) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TAC1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TAC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the TAC1 tac1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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