Western Blot (WB)
(Western blot analysis of extracts of 293 cell lines, using TAC1 antibody.)
Rabbit TAC1 Polyclonal Antibody | anti-TAC1 antibody
TAC1 (Tachykinin, Precursor 1, NK2, NPK, NKNA, TAC2, Hs.2563) (PE)
WB: 1:500-1:2000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of extracts of 293 cell lines, using TAC1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of 293 cell lines, using TAC1 antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
Uniprot Description
TAC1: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 7q21-q22
Cellular Component: extracellular space; cell soma; axon; extracellular region; plasma membrane
Molecular Function: protein binding; substance P receptor binding
Biological Process: tachykinin signaling pathway; negative regulation of heart rate; insemination; response to hormone stimulus; response to morphine; response to lipopolysaccharide; response to pain; sensory perception of pain; positive regulation of saliva secretion; synaptic transmission; elevation of cytosolic calcium ion concentration; cell-cell signaling; positive regulation of acute inflammatory response; positive regulation of lymphocyte proliferation; neuropeptide signaling pathway; regulation of blood pressure; positive regulation of stress fiber formation; positive regulation of action potential; inflammatory response; associative learning; detection of abiotic stimulus; positive regulation of synaptic transmission, cholinergic; positive regulation of synaptic transmission, GABAergic; positive regulation of ossification; long-term memory
Research Articles on TAC1
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Product Notes
The TAC1 tac1 (Catalog #AAA6439849) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TAC1 (Tachykinin, Precursor 1, NK2, NPK, NKNA, TAC2, Hs.2563) (PE) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TAC1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC: 1:50-1:200 WB: 1:500-1:2000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TAC1 tac1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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