Rabbit anti-Human TAAR5 Polyclonal Antibody | anti-TAAR5 antibody

TAAR5 Antibody (C-term)

Cat. Num. AAA9204661

• Gene Names: TAAR5; PNR
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: TAAR5; Polyclonal Antibody; TAAR5 Antibody (C-term); Trace amine-associated receptor 5; TaR-5; Trace amine receptor 5; hTaar5; Putative neurotransmitter receptor; PNR; anti-TAAR5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This TAAR5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 236-269 amino acids from the C-terminal region of human TAAR5.
• Purity/Purification: Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Vial Concentration: 0.5 (varies by lot)
• Sequence Length: 337

• Applicable Applications for anti-TAAR5 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB~~1:2000
• Antigen Source: HUMAN
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-TAAR5 Antibody (C-term)at 1:2000 dilution + SH-SY5Y whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 38 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Related Product Information for anti-TAAR5 antibody

Olfactory receptor specific for trimethylamine, a trace amine. Also activated at lower level by dimethylethylamine. Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase.

References

Zeng Z.,et al.Biochem. Biophys. Res. Commun. 242:575-578(1998).
Lindemann L.,et al.Genomics 85:372-385(2005).
Staubert C.,et al.PLoS ONE 5:E11133-E11133(2010).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

• NCBI GI #: 223633986
• NCBI GeneID: 9038
• NCBI Accession #: NP_003958.2
• NCBI GenBank Nucleotide #: NM_003967.2
• UniProt Accession #: O14804; Q2M1V1; Q4VBL1; Q5VUQ3; Q6NTA8; D8KZS1
• Molecular Weight: 38242
• NCBI Official Full Name: trace amine-associated receptor 5
• NCBI Official Synonym Full Names: trace amine associated receptor 5
• NCBI Official Symbol: TAAR5
• NCBI Official Synonym Symbols: PNR
• NCBI Protein Information: trace amine-associated receptor 5
• UniProt Protein Name: Trace amine-associated receptor 5
• Protein Family: Trace amine-associated receptor
• UniProt Gene Name: TAAR5
• UniProt Synonym Gene Names: PNR; TaR-5; Trace amine receptor 5; hTaar5
• UniProt Entry Name: TAAR5_HUMAN

Uniprot Description

TAAR5: Orphan receptor. Ligands are likely small molecules, either sharing some similarities with trace amine as, e.g. derivatives of indolamines (such as 5-methoxytryptamine) or of phenylethylamines (such as phenylethanolamine) or being any kind of metabolite of amino acids or biogenic amine neurotransmitters. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q23

Cellular Component: integral to plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; synaptic transmission; sensory perception of chemical stimulus; signal transduction