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Immunohistochemistry (IHC) (Anti-TAAR1 antibody IHC of human brain, amygdala. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit TAAR1 / TA1 Polyclonal Antibody | anti-TAAR1 antibody

Rabbit Polyclonal to Human TAAR1 / TA1

Gene Names
TAAR1; TA1; TAR1; TRAR1
Reactivity
Gibbon, Chimpanzee, Human, Monkey
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
TAAR1 / TA1; Polyclonal Antibody; Rabbit Polyclonal to Human TAAR1 / TA1; Anti-TAAR1 / TA1 Antibody (N-Terminus) IHC-plus; TAAR1; RP11-295F4.9; RTAR1; Snorf33; TRAR1; TaR-1; TAR1; TA1; Trace amine receptor 1; Human TAAR1; anti-TAAR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Chimpanzee, Human, Monkey
Clonality
Polyclonal
Specificity
Human TAAR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
339
Applicable Applications for anti-TAAR1 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (1.3 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from N-terminus of human TAAR1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Tamarin (100%); Orangutan, Cat, Horse (88%); Bovine, Elephant, Panda, Rabbit, Pig (81%).
Immunogen Type
Synthetic peptide
Immunogen
TAAR1 / TA1 antibody was raised against synthetic 16 amino acid peptide from N-terminus of human TAAR1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Tamarin (100%); Orangutan, Cat, Horse (88%); Bovine, Elephant, Panda, Rabbit, Pig (81%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-TAAR1 antibody IHC of human brain, amygdala. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-TAAR1 antibody IHC of human brain, amygdala. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-TAAR1 antibody
TAAR1/TA1 is a Trace Amine Receptor activated by tyramine and beta-PEA. TAAR1/TA1 is likely to be involved in regulation of blood pressure, electrolyte homeostasis, and in controlling mood. An allelic variant of TAAR1/TA1 has been identified.
Product Categories/Family for anti-TAAR1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,092 Da
NCBI Official Full Name
trace amine-associated receptor 1
NCBI Official Synonym Full Names
trace amine associated receptor 1
NCBI Official Symbol
TAAR1
NCBI Official Synonym Symbols
TA1; TAR1; TRAR1
NCBI Protein Information
trace amine-associated receptor 1; taR-1; trace amine receptor 1
UniProt Protein Name
Trace amine-associated receptor 1
UniProt Gene Name
TAAR1
UniProt Synonym Gene Names
TA1; TAR1; TRAR1; TaR-1; Trace amine receptor 1
UniProt Entry Name
TAAR1_HUMAN

NCBI Description

TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 [PubMed 11723224]).[supplied by OMIM, Mar 2008]

Uniprot Description

TAAR1: Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; trace-amine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on TAAR1

Similar Products

Product Notes

The TAAR1 taar1 (Catalog #AAA242741) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human TAAR1 / TA1 reacts with Gibbon, Chimpanzee, Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's TAAR1 / TA1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (1.3 ug/ml). Researchers should empirically determine the suitability of the TAAR1 taar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAAR1 / TA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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