Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SYNE3 antibody.)
Rabbit anti-Human SYNE3 Polyclonal Antibody | anti-SYNE3 antibody
SYNE3 Polyclonal Antibody
Gene Names
SYNE3; KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purification
Synonyms
SYNE3; Polyclonal Antibody; SYNE3 Polyclonal Antibody; C14orf49; Chromosome 14 open reading frame 49; FLJ25605; MGC75267; Nesp3; Nesprin 3; Nesprin-3; NET53; Nuclear Envelope Spectrin Repeat Protein 3; Spectrin Repeat Containing; Nuclear Envelope Family Member 3; anti-SYNE3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1 mg/mL (varies by lot)
Sequence Length
970
Applicable Applications for anti-SYNE3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human SYNE3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SYNE3 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SYNE3 antibody.)
Product Categories/Family for anti-SYNE3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 68kDa; 111kDa; 112kDa
Observed: 112kDa
Observed: 112kDa
NCBI Official Full Name
nesprin-3 isoform 1
NCBI Official Synonym Full Names
spectrin repeat containing nuclear envelope family member 3
NCBI Official Symbol
SYNE3
NCBI Official Synonym Symbols
KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341
NCBI Protein Information
nesprin-3
UniProt Protein Name
Nesprin-3
Protein Family
UniProt Gene Name
SYNE3
UniProt Synonym Gene Names
KASH3
Uniprot Description
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Research Articles on SYNE3
Similar Products
Product Notes
The SYNE3 syne3 (Catalog #AAA2554887) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYNE3 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SYNE3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the SYNE3 syne3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYNE3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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