Testing Data
(SPC3 labeled with mouse pachytene preparation (red), using S9106-92B CDK2 staining, near teleomeresis also present (green).)
Rabbit anti-Mouse Synaptonemal Complex Protein 3 Polyclonal Antibody | anti-SYCP3 antibody
Synaptonemal Complex Protein 3 (SCP3, SCP-3, SYCP3, COR1, MGC71888, RNASCP3) (HRP)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: Immunoflourescence: 1:100-1:750
Immunohistochemistry (paraffin): 1:750
Optimal dilutions to be determined by researcher.
Testing Data
(SPC3 labeled with mouse pachytene preparation (red), using S9106-92B CDK2 staining, near teleomeresis also present (green).)
Testing Data
(SPC3 labeled with mouse pachytene preparation (red), using S9106-92B CDK2 staining, near teleomeresis also present (green).)
Testing Data
(Punctate staining of murine SCP3 in mouse ovary using S9106-92B.)
Testing Data
(Punctate staining of murine SCP3 in mouse ovary using S9106-92B.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq]
Uniprot Description
SYCP3: Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Defects in SYCP3 are the cause of spermatogenic failure type 4 (SPGF4). An infertility disorder characterized by azoospermia, a condition of having no sperm present in the ejaculate. Testicular histology shows arrest of spermatogenesis at the pachytene stage of primary spermatocytes. Belongs to the XLR/SYCP3 family.
Chromosomal Location of Human Ortholog: 12q
Cellular Component: chromosome; nucleus
Molecular Function: DNA binding
Biological Process: male meiosis I; cell division; spermatogenesis, exchange of chromosomal proteins
Disease: Spermatogenic Failure 4
Research Articles on SYCP3
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Product Notes
The SYCP3 sycp3 (Catalog #AAA621998) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Synaptonemal Complex Protein 3 (SCP3, SCP-3, SYCP3, COR1, MGC71888, RNASCP3) (HRP) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Synaptonemal Complex Protein 3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF). Suitable for use in Immunoflourescence and Immunohistochemistry. Dilution: Immunoflourescence: 1:100-1:750 Immunohistochemistry (paraffin): 1:750 Optimal dilutions to be determined by researcher. Researchers should empirically determine the suitability of the SYCP3 sycp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Synaptonemal Complex Protein 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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