Goat Synaptogyrin 3 Polyclonal Antibody | anti-SYNGR3 antibody
Goat anti-Synaptogyrin 3 Antibody
Western Blot: Preliminary experiments gave an approx 50kDa band in Human and Mouse Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 24.6kDa according to NP_004200. The 50kDa band was successfully blocked by incubation with the immunizing peptide.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an integral membrane protein. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it is a synaptic vesicle protein that also interacts with the dopamine transporter. The gene product belongs to the synaptogyrin gene family. [provided by RefSeq, Dec 2010]
Uniprot Description
SYNGR3: Involved in the positive regulation of dopamine transporter activity. Probably facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release. Belongs to the synaptogyrin family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16p13
Cellular Component: cell junction; integral to membrane; neuromuscular junction; synaptic vesicle; synaptic vesicle membrane
Molecular Function: protein N-terminus binding; SH2 domain binding
Biological Process: positive regulation of transporter activity; substantia nigra development
Research Articles on SYNGR3
Similar Products
Product Notes
The SYNGR3 syngr3 (Catalog #AAA420626) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Synaptogyrin 3 Antibody reacts with Expected from sequence similarity: Human, Rat, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's Synaptogyrin 3 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Preliminary experiments gave an approx 50kDa band in Human and Mouse Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 24.6kDa according to NP_004200. The 50kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the SYNGR3 syngr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: QRTAPGPATT QAGD. It is sometimes possible for the material contained within the vial of "Synaptogyrin 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
