Western Blot (WB)
(SYN3 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (15ug/lane).This demonstrates the SYN3 antibody detected the SYN3 protein (arrow).)
Rabbit anti-Human SYN3 Polyclonal Antibody | anti-SYN3 antibody
SYN3, ID (SYN3, Synapsin-3, Synapsin III)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Western Blot (WB)
(SYN3 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (15ug/lane).This demonstrates the SYN3 antibody detected the SYN3 protein (arrow).)
Western Blot (WB)
(SYN3 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (15ug/lane).This demonstrates the SYN3 antibody detected the SYN3 protein (arrow).)
Immunohistochemistry (IHC)
(SYN3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SYN3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(SYN3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SYN3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq, Oct 2008]
Uniprot Description
SYN3: neuronal phosphoprotein that may be involved in the regulation of neurotransmitter release and synaptogenesis. Binds ATP with high affinity and ADP with a lower affinity. This is consistent with a catalytic role of the C-domain in which ADP would be dissociated by cellular ATP after bound ATP was hydrolyzed. May represent a candidate gene for schizophrenia. Alternative splicing results in six variants; however, only three isoforms have been fully described.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 22q12.3
Cellular Component: synaptic vesicle; synaptic vesicle membrane; cell junction
Molecular Function: catalytic activity; ATP binding
Biological Process: metabolic process; neurotransmitter secretion; regulation of synaptic transmission, GABAergic
Research Articles on SYN3
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Product Notes
The SYN3 syn3 (Catalog #AAA6010786) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYN3, ID (SYN3, Synapsin-3, Synapsin III) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SYN3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100. Researchers should empirically determine the suitability of the SYN3 syn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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