Rabbit anti-Human SYN2 Polyclonal Antibody | anti-SYN2 antibody
SYN2 Antibody
Immunohistochemistry: 1:50-1:200
Testing Data
(Gel: 6%SDS-PAGE Lysates (from left to right): Hela, A375 and LoVo cell Amount of lysate: 40ug per lane Primary antibody: 1/1400 dilution Secondary antibody dilution: 1/8000 Exposure time: 40 seconds)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/40.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction. [provided by RefSeq, Feb 2014]
Uniprot Description
SYN2: neuronal phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal and to the cytoskeleton. May function in the regulation of neurotransmitter release and synaptogenesis. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing results in two isoforms.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 3p25
Cellular Component: synaptic vesicle membrane; synapse; cell junction
Molecular Function: catalytic activity; ATP binding
Biological Process: synaptic transmission; metabolic process; neurotransmitter secretion
Disease: Schizophrenia
Research Articles on SYN2
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Product Notes
The SYN2 syn2 (Catalog #AAA9409721) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYN2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SYN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:1000-1:5000 Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the SYN2 syn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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