Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SYCP1 Polyclonal Antibody at dilution 1:35)
Rabbit SYCP1 Polyclonal Antibody | anti-SYCP1 antibody
SYCP1 Polyclonal Antibody
Gene Names
SYCP1; CT8; SCP1; SCP-1; HOM-TES-14
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
SYCP1; Polyclonal Antibody; SYCP1 Polyclonal Antibody; CT8; SCP1; SCP-1; HOM-TES-14; anti-SYCP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.4mg/mL (varies by lot)
Sequence Length
951
Applicable Applications for anti-SYCP1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human SYCP1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SYCP1 Polyclonal Antibody at dilution 1:35)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SYCP1 Polyclonal Antibody at dilution 1:35)
Related Product Information for anti-SYCP1 antibody
The synaptonemal complex protein 1 (SCP-1), also known as SYCP1(A), SYN1(I) and HOM-TES-14, is a protein product of human chromosome 1p13-p12. SCP-1 is a major component of the transverse filaments of synaptonemal complexes and functions by pairing homologous chromosomes during meiotic prophase in spermatocytes, which is an essential step for the generation of haploid cells in meiosis I. SCP-1 is expressed in the testis, adult brain, some malignant gliomas, breast, renal cell and ovarian cancer. SCP-1 is known to be selectively expressed during the meiotic prophase of spermatocytes and shows cell cycle phase-independent nuclear expression in cancer cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
114,192 Da
NCBI Official Full Name
synaptonemal complex protein 1 isoform 2
NCBI Official Synonym Full Names
synaptonemal complex protein 1
NCBI Official Symbol
SYCP1
NCBI Official Synonym Symbols
CT8; SCP1; SCP-1; HOM-TES-14
NCBI Protein Information
synaptonemal complex protein 1; cancer/testis antigen 8
UniProt Protein Name
Synaptonemal complex protein 1
Protein Family
UniProt Gene Name
SYCP1
UniProt Synonym Gene Names
SCP1; SCP-1; CT8
UniProt Entry Name
SYCP1_HUMAN
Uniprot Description
SYCP1: Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.
Protein type: Cancer Testis Antigen (CTA); DNA-binding
Chromosomal Location of Human Ortholog: 1p13-p12
Cellular Component: male germ cell nucleus; transverse filament; central element
Molecular Function: DNA binding
Biological Process: synaptonemal complex assembly; regulation of protein localization; sperm chromatin condensation; cell division; meiotic recombination; meiotic DNA repair synthesis; lateral element assembly; spermatogenesis; chiasma formation
Research Articles on SYCP1
Similar Products
Product Notes
The SYCP1 sycp1 (Catalog #AAA2519378) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYCP1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SYCP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:25-1:100. Researchers should empirically determine the suitability of the SYCP1 sycp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYCP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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