Rabbit anti-Human Suppressors Of Cytokine Signaling 1 (SOCS1) Polyclonal Antibody | anti-SOCS1 antibody

HRP-Linked Polyclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1)

Cat. Num. AAA2110582

• Gene Names: SOCS1; JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; TIP-3; SOCS-1
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
• Purity: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Synonyms: Suppressors Of Cytokine Signaling 1 (SOCS1); Polyclonal Antibody; HRP-Linked Polyclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1); CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP3; JAK-binding protein; STAT-induced STAT inhibitor 1; Tec-interacting protein 3; anti-SOCS1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody is a Rabbit polyclonal antibody raised against SOCS1. It has been selected for its ability to recognize SOCS1 in immunohistochemical staining and western blotting.
• Purity/Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Form/Format: Liquid
• Concentration: 500ug/ml (varies by lot)
• Sequence: RPH158Hu01-Recombinant Suppressors Of Cytokine Signaling 1 (SOCS1)
• Sequence Length: 211

• Applicable Applications for anti-SOCS1 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
• Conjugation: HRP
• Cross Reactivity: Human
• Preparation and Storage: Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.; Avoid repeated freeze/thaw cycles.; ; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

NCBI and Uniprot Product Information

• NCBI GI #: 4507233
• NCBI GeneID: 8651
• NCBI Accession #: NP_003736.1
• NCBI GenBank Nucleotide #: NM_003745.1
• UniProt Accession #: O15524
• NCBI Official Full Name: suppressor of cytokine signaling 1
• NCBI Official Synonym Full Names: suppressor of cytokine signaling 1
• NCBI Official Symbol: SOCS1
• NCBI Official Synonym Symbols: JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; TIP-3; SOCS-1
• NCBI Protein Information: suppressor of cytokine signaling 1
• UniProt Protein Name: Suppressor of cytokine signaling 1
• Protein Family: Suppressor of cytokine signaling
• UniProt Gene Name: SOCS1
• UniProt Synonym Gene Names: SSI1; TIP3; SOCS-1; JAB; SSI-1; TIP-3
• UniProt Entry Name: SOCS1_HUMAN

NCBI Description

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]