Western Blot (WB)
(Western blot analysis of SUN1 expression in Ramos cell lysate.)
Rabbit anti-Human SUN1 Polyclonal Antibody | anti-SUN1 antibody
SUN1 Rabbit pAb
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
FC/FACS: 1:50
Western Blot (WB)
(Western blot analysis of SUN1 expression in Ramos cell lysate.)
Western Blot (WB)
(Western blot analysis of SUN1 expression in Ramos cell lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2010]
Uniprot Description
SUN1: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non- coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs). 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cytoskeletal
Chromosomal Location of Human Ortholog: 7p22.3
Cellular Component: nuclear membrane; intracellular membrane-bound organelle; integral to nuclear inner membrane; nuclear envelope; acrosomal membrane
Molecular Function: protein binding; lamin binding
Biological Process: nuclear membrane organization and biogenesis
Research Articles on SUN1
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Product Notes
The SUN1 sun1 (Catalog #AAA4755807) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SUN1 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SUN1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS). WB: 1:500-1:2000 IHC: 1:50-1:200 ICC/IF: 1:50-1:200 FC/FACS: 1:50. Researchers should empirically determine the suitability of the SUN1 sun1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SUN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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