Goat anti-Human SULT4A1 Polyclonal Antibody | anti-SULT4A1 antibody

SULT4A1 (sulfotransferase family 4A, Member 1, Brain sulfotransferase-like protein, Nervous system sulfotransferase, brain sulphotransferase-like, nervous system cytosolic sulfotransferase, sulfotransferase-related protein)

Cat. Num. AAA622667

• Gene Names: SULT4A1; NST; BRSTL1; SULTX3; BR-STL-1; MGC40032; DJ388M5.3; hBR-STL-1
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunoprecipitation
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: SULT4A1; Polyclonal Antibody; SULT4A1 (sulfotransferase family 4A; Member 1; Brain sulfotransferase-like protein; Nervous system sulfotransferase; brain sulphotransferase-like; nervous system cytosolic sulfotransferase; sulfotransferase-related protein); Anti -SULT4A1 (sulfotransferase family 4A; anti-SULT4A1 antibody

• Host: Goat
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SULT4A1. Species sequence homology: mouse (98%).
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a lyophilized powder from 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS, sterile 40-50% glycerol.

• Applicable Applications for anti-SULT4A1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
• Application Notes: Suitable for use in ELISA, Western Blot, and Immunoprecipitation.; Dilution: ELISA: 0.5-1ug/ml; Western Blot: 1ug/ml
• Immunogen: E. coli-derived, recombinant human Cytosolic Sulfotransferase 4A1 isoform 1 (aa2-284).
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS, sterile 40-50% glycerol, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

SDS-Page

(Detection of SULT4A1 with MBS622667. Tissue lysates were resolved by SDS-PAGE, transferred to an Immobilon-P membrane and immunoblotted with 1ug/ml goat anti-hSULT4A1.)

Related Product Information for anti-SULT4A1 antibody

SULT4A1 (Cytosolic Sulfotransferase 4A1; also BR-STL1/Brain sulfotransferase-like protein) is a 33-36kD member of the sulfotransferase 4 family of enzymes. SULT4A1 message is widely expressed. However, it appears to be translated only in brain. SULT4A1 is very unusual in that it is the only SULT that shows minimal activity on synthetic laboratory substrates. Instead, it acts on catecholamines and T4 in a manner that may not involve sulfonation. Human SULT4A1 is 284aa in length. A weak PAPS binding site is found between aa246-254. There are two potential isoforms, one that shows a 13aa substitution for aa248-284, and a second that contains a 48aa substitution for aa202-247. Full-length human SULT4A1 is 98% aa identical to mouse SULT4A1.

Product Categories/Family for anti-SULT4A1 antibody

Antibodies; Abs to Enzymes; Sulfotransferase

NCBI and Uniprot Product Information

• NCBI GI #: 7657633
• NCBI GeneID: 25830
• NCBI Accession #: NP_055166.1
• NCBI GenBank Nucleotide #: NM_014351.3
• UniProt Accession #: Q9BR01; O43728; B2R7N3
• Molecular Weight: 33,085 Da
• NCBI Official Full Name: sulfotransferase 4A1
• NCBI Official Synonym Full Names: sulfotransferase family 4A, member 1
• NCBI Official Symbol: SULT4A1
• NCBI Official Synonym Symbols: NST; BRSTL1; SULTX3; BR-STL-1; MGC40032; DJ388M5.3; hBR-STL-1
• NCBI Protein Information: sulfotransferase 4A1; ST4A1; hBR-STL; OTTHUMP00000180667; OTTHUMP00000197813; nervous system sulfotransferase; sulfotransferase-related protein; brain sulfotransferase-like protein; nervous system cytosolic sulfotransferase
• UniProt Protein Name: Sulfotransferase 4A1
• Protein Family: Sulfotransferase
• UniProt Gene Name: SULT4A1
• UniProt Synonym Gene Names: SULTX3
• UniProt Entry Name: ST4A1_HUMAN

NCBI Description

This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia. [provided by RefSeq]

Uniprot Description

SULT4A1: Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.8.2.-; Transferase

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: cytosol

Molecular Function: sulfotransferase activity; protein binding

Biological Process: steroid metabolic process; xenobiotic metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process