Rabbit anti-Rat Sulfite Oxidase (SUOX) Polyclonal Antibody | anti-SUOX antibody

Biotin-Linked Antibody to Sulfite Oxidase (SUOX)

Cat. Num. AAA2007334

• Reactivity: Rat
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Affinity Chromatography
• Synonyms: Sulfite Oxidase (SUOX); Polyclonal Antibody; Biotin-Linked Antibody to Sulfite Oxidase (SUOX); anti-SUOX antibody

• Host: Rabbit
• Reactivity: Rat
• Clonality: Polyclonal
• Specificity: The antibody is a rabbit polyclonal antibody raised against SUOX conjugated to biotin. It has been selected for its ability to recognize SUOX in immunohistochemical staining andwestern blotting.
• Purity/Purification: Affinity Chromatography
• Form/Format: Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
• Concentration: 500ug/ml (varies by lot)
• Sequence Length: 488

• Applicable Applications for anti-SUOX antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: Western blotting: 1:100-400; Immunocytochemistry in formalin fixed cells: 1:100-500; Immunohistochemistry in formalin fixed frozen section: 1:100-500; Immunohistochemistry in paraffin section: 1:50-200; Enzyme-linked Immunosorbent Assay: 1:100-200
• Preparation and Storage: Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Product Categories/Family for anti-SUOX antibody

Biotin Antibody

NCBI and Uniprot Product Information

• NCBI GI #: 508502
• NCBI GeneID: 6821
• UniProt Accession #: P51687
• Molecular Weight: 60,283 Da
• NCBI Official Full Name: sulfite oxidase
• NCBI Official Synonym Full Names: sulfite oxidase
• NCBI Official Symbol: SUOX
• NCBI Protein Information: sulfite oxidase, mitochondrial
• UniProt Protein Name: Sulfite oxidase, mitochondrial
• Protein Family: Sulfite oxidase
• UniProt Gene Name: SUOX
• UniProt Entry Name: SUOX_HUMAN

NCBI Description

Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008]

Uniprot Description

SUOX: Defects in SUOX are the cause of isolated sulfite oxidase deficiency (ISOD); also known as sulfocysteinuria. ISOD is characterized by neurological abnormalities including multicystic leukoencephalopathy with brain atrophy. Patients often suffer from seizures. Often leads to death at an early age.

Protein type: Energy Metabolism - sulfur; Oxidoreductase; EC 1.8.3.1; Mitochondrial

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: mitochondrial matrix; mitochondrial intermembrane space

Molecular Function: molybdopterin cofactor binding; electron carrier activity; molybdenum ion binding; heme binding; sulfite oxidase activity

Biological Process: sulfur amino acid metabolic process; sulfur amino acid catabolic process

Disease: Sulfocysteinuria