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Western Blot (WB) (All lanes: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial antibody at 2ug/ml+Hela whole cell lysate)

Rabbit anti-Human Succinyl-CoA:3-ketoacid coenzyme A transferase 1 Polyclonal Antibody | anti-OXCT1 antibody

Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial Polyclonal Antibody

Gene Names
OXCT1; OXCT; SCOT
Reactivity
Human
Applications
Western Blot
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Succinyl-CoA:3-ketoacid coenzyme A transferase 1; Polyclonal Antibody; mitochondrial Polyclonal Antibody; 3-oxoacid CoA-transferase 1 Somatic-type succinyl-CoA:3-oxoacid CoA-transferase OXCT1 OXCT; SCOT; anti-OXCT1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
520
Applicable Applications for anti-OXCT1 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:500 - 1:1000
Immunogen
Recombinant Human Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(All lanes: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial antibody at 2ug/ml+Hela whole cell lysate)

Western Blot (WB) (All lanes: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial antibody at 2ug/ml+Hela whole cell lysate)
Related Product Information for anti-OXCT1 antibody
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Product Categories/Family for anti-OXCT1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13,358 Da
NCBI Official Full Name
succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
NCBI Official Synonym Full Names
3-oxoacid CoA-transferase 1
NCBI Official Symbol
OXCT1
NCBI Official Synonym Symbols
OXCT; SCOT
NCBI Protein Information
succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
UniProt Protein Name
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
UniProt Gene Name
OXCT1
UniProt Synonym Gene Names
OXCT; SCOT; SCOT-s
UniProt Entry Name
SCOT1_HUMAN

Uniprot Description

OXCT1: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. Defects in OXCT1 are a cause of succinyl-CoA-3-ketoacid- CoA transferase deficiency (SCOTD). A disorder of ketone body metabolism, characterized by episodic ketoacidosis. Patients are usually asymptomatic between episodes. Belongs to the 3-oxoacid CoA-transferase family.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - butanoate; EC 2.8.3.5; Lipid Metabolism - synthesis and degradation of ketone bodies; Mitochondrial; Transferase

Chromosomal Location of Human Ortholog: 5p13.1

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: 3-oxoacid CoA-transferase activity

Biological Process: ketone body catabolic process; ketone body metabolic process

Disease: Succinyl-coa:3-oxoacid Coa Transferase Deficiency

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Product Notes

The OXCT1 oxct1 (Catalog #AAA9415985) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Succinyl-CoA:3-ketoacid coenzyme A transferase 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500 - 1:1000. Researchers should empirically determine the suitability of the OXCT1 oxct1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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