Rabbit anti-Human STXBP3 Polyclonal Antibody | anti-STXBP3 antibody

STXBP3, ID (STXBP3, Syntaxin-binding protein 3, Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C) (PE)

Cat. Num. AAA6352422

• Gene Names: STXBP3; PSP; MUNC18C; UNC-18C; MUNC18-3
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: STXBP3; Polyclonal Antibody; ID (STXBP3; Syntaxin-binding protein 3; Platelet Sec1 protein; Protein unc-18 homolog 3; Protein unc-18 homolog C) (PE); Protein unc-18 homolog C; anti-STXBP3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-STXBP3 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:10-50; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: STXBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-171 amino acids from the Central region of human STXBP3.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(STXBP3 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the STXBP3 antibody detected the STXBP3 protein (arrow).)

Immunohistochemistry (IHC)

(STXBP3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STXBP3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-STXBP3 antibody

Together with STX4 and VAMP2, STXBP3 may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity).

Product Categories/Family for anti-STXBP3 antibody

Antibodies; Syntaxin; Synaptotagmin; Synaptophysin

References

Bostrom, P., et al. Diabetes 59(8):1870-1878(2010). Ban, H.J., et al. BMC Genet. 11, 26 (2010): Brochetta, C., et al. Biochim. Biophys. Acta 1783(10):1781-1791(2008). Smithers, N.P., et al. J. Recept. Signal Transduct. Res. 28(6):581-589(2008). Fu, J., et al. J. Biol. Chem. 280(5):3178-3184(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 118600975
• NCBI GeneID: 6814
• NCBI Accession #: NP_009200.2
• NCBI GenBank Nucleotide #: NM_007269.2
• UniProt Accession #: O00186; Q53FW1; Q86YJ3; Q9UPD7; A8K269; A8K5K7
• Molecular Weight: 67,764 Da
• NCBI Official Full Name: syntaxin-binding protein 3
• NCBI Official Synonym Full Names: syntaxin binding protein 3
• NCBI Official Symbol: STXBP3
• NCBI Official Synonym Symbols: PSP; MUNC18C; UNC-18C; MUNC18-3
• NCBI Protein Information: syntaxin-binding protein 3
• UniProt Protein Name: Syntaxin-binding protein 3
• Protein Family: Syntaxin-binding protein
• UniProt Gene Name: STXBP3
• UniProt Synonym Gene Names: PSP; Unc18-3; Unc-18C
• UniProt Entry Name: STXB3_HUMAN