Rabbit anti-Human, Mouse STX5 Polyclonal Antibody | anti-STX5 antibody

STX5, ID (STX5, STX5A, Syntaxin-5) (MaxLight 750)

Cat. Num. AAA6352377

• Gene Names: STX5; SED5; STX5A
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: STX5; Polyclonal Antibody; ID (STX5; STX5A; Syntaxin-5) (MaxLight 750); Syntaxin-5; anti-STX5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

• Applicable Applications for anti-STX5 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: STX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-209 amino acids from the Central region of human STX5.
• Conjugate: MaxLight750
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-STX5 antibody

STX5 mediates endoplasmic reticulum to Golgi transport (By similarity).

Product Categories/Family for anti-STX5 antibody

Antibodies; Syntaxin; Synaptotagmin; Synaptophysin

References

Laufman, O., et al. EMBO J. 28(14):2006-2017(2009). Diao, A., et al. J. Biol. Chem. 283(11):6957-6967(2008). Amessou, M., et al. J. Cell. Sci. 120 (PT 8), 1457-1468 (2007): Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006). Suga, K., et al. FEBS Lett. 579(20):4226-4234(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 94400932
• NCBI GeneID: 6811
• NCBI Accession #: NP_003155.2
• NCBI GenBank Nucleotide #: NM_003164.4
• UniProt Accession #: Q13190; Q5U0D4; Q7Z3T6; Q9BUG1; B2R8T2; F8W8Q9
• Molecular Weight: 35,474 Da
• NCBI Official Full Name: syntaxin-5 isoform 1
• NCBI Official Synonym Full Names: syntaxin 5
• NCBI Official Symbol: STX5
• NCBI Official Synonym Symbols: SED5; STX5A
• NCBI Protein Information: syntaxin-5; syntaxin 5A
• UniProt Protein Name: Syntaxin-5
• Protein Family: Syntaxin
• UniProt Gene Name: STX5
• UniProt Synonym Gene Names: STX5A

NCBI Description

This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Uniprot Description

Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus.