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Immunohistochemistry (IHC) (Immunochemical staining of human STRA8 in human testis with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).)

Rabbit anti-Human STRA8 Polyclonal Antibody | anti-STRA8 antibody

Anti-STRA8 Antibody, Rabbit Polyclonal

Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
STRA8; Polyclonal Antibody; Anti-STRA8 Antibody; Rabbit Polyclonal; STRA8 Antibody; Rabbit PAb; Antigen Affinity Purified; stimulated by retinoic acid gene 8; anti-STRA8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human STRA8
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-STRA8 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:250-1:1000
Immunogen
A synthetic peptide corresponding to the N-terminus of the Human STRA8
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human STRA8, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunochemical staining of human STRA8 in human testis with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).)

Immunohistochemistry (IHC) (Immunochemical staining of human STRA8 in human testis with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-STRA8 antibody
Stimulated by retinoic acid gene 8 (STRA8) is specifically expressed in mammalian germ cells before their transition from mitosis to meiosis. STRA8 expression is observed only in the postnatal testis. Stra8 (stimulated by retinoic acid 8) encodes a protein crucial for mammalian germ cells entering into premeiotic stages. STRA8 associates with DNA and possesses transcriptional activity, and STRA8 can exert important functions in the nucleus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
36,908 Da
NCBI Official Full Name
Stimulated by retinoic acid gene 8 protein homolog
NCBI Official Synonym Full Names
stimulated by retinoic acid 8
NCBI Official Symbol
STRA8
NCBI Protein Information
stimulated by retinoic acid gene 8 protein homolog; STRA8 {ECO:0000312|EMBL:AAP47163.1}; stimulated by retinoic acid 8 homolog; stimulated by retinoic acid gene 8 homolog
UniProt Protein Name
Stimulated by retinoic acid gene 8 protein homolog
UniProt Gene Name
STRA8
UniProt Entry Name
STRA8_HUMAN

NCBI Description

This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010]

Uniprot Description

STRA8: Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase.

Chromosomal Location of Human Ortholog: 7q33

Cellular Component: cytoplasm; nucleus

Molecular Function: protein dimerization activity

Biological Process: fertilization; meiotic cell cycle DNA replication checkpoint; ovarian follicle development; meiotic chromosome condensation; meiotic recombination; synapsis; meiotic DNA double-strand break formation; spermatogenesis; regulation of organ growth; female meiosis sister chromatid cohesion; DNA replication; oocyte development

Research Articles on STRA8

Similar Products

Product Notes

The STRA8 stra8 (Catalog #AAA8100276) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-STRA8 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STRA8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:250-1:1000. Researchers should empirically determine the suitability of the STRA8 stra8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STRA8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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