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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7050968 at dilution of 1:100)

Rabbit anti-Human STMN2 Polyclonal Antibody | anti-STMN2 antibody

STMN2 Antibody

Gene Names
STMN2; SCG10; SCGN10
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
STMN2; Polyclonal Antibody; STMN2 Antibody; Stathmin-2; Superior cervical ganglion-10 protein; Protein SCG10; SCG10; SCGN10; anti-STMN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
187
Applicable Applications for anti-STMN2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1: 20-1: 200
IF: 1: 50-1: 200
Immunogen
Recombinant Human Stathmin-2 protein (61-129AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-49258
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7050968 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7050968 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7050968 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7050968 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of A549 cells using MBS7050968 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunohistochemistry (IHC) (Immunofluorescent analysis of A549 cells using MBS7050968 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-STMN2 antibody
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,802 Da
NCBI Official Full Name
stathmin-2 isoform 1
NCBI Official Synonym Full Names
stathmin 2
NCBI Official Symbol
STMN2
NCBI Official Synonym Symbols
SCG10; SCGN10
NCBI Protein Information
stathmin-2
UniProt Protein Name
Stathmin-2
Protein Family
UniProt Gene Name
STMN2
UniProt Synonym Gene Names
SCG10; SCGN10; Protein SCG10
UniProt Entry Name
STMN2_HUMAN

NCBI Description

This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010]

Uniprot Description

STMN2: a cytoskeletal protein that may play a role in neuronal differentiation, and in modulating membrane interaction with the cytoskeleton during neurite outgrowth. Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. Neuron specific.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 8q21.13

Cellular Component: cell soma; cytoplasm; growth cone; lamellipodium; neuron projection; perinuclear region of cytoplasm

Molecular Function: calcium-dependent protein binding; protein binding; tubulin binding

Biological Process: negative regulation of microtubule depolymerization; negative regulation of microtubule polymerization; positive regulation of microtubule depolymerization

Research Articles on STMN2

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Product Notes

The STMN2 stmn2 (Catalog #AAA7050968) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STMN2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STMN2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1: 20-1: 200 IF: 1: 50-1: 200. Researchers should empirically determine the suitability of the STMN2 stmn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STMN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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