Rabbit STK38L Polyclonal Antibody | anti-STK38L antibody

STK38L Rabbit Polyclonal

Cat. Num. AAA7604571

• Gene Names: STK38L; NDR2
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: STK38L; Polyclonal Antibody; STK38L Rabbit Polyclonal; anti-STK38L antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 464

• Applicable Applications for anti-STK38L antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: Serine/threonine kinase 38 like
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat heart using MBS7604571 (STK38L antibody) at dilution of 1:50)

Western Blot (WB)

(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7604571 (STK38L antibody) at dilution of 1:800)

NCBI and Uniprot Product Information

• NCBI GI #: 24307971
• NCBI GeneID: 23012
• NCBI Accession #: NP_055815.1
• NCBI GenBank Nucleotide #: NM_015000.3
• Molecular Weight: 43,170 Da
• NCBI Official Full Name: serine/threonine-protein kinase 38-like
• NCBI Official Synonym Full Names: serine/threonine kinase 38 like
• NCBI Official Symbol: STK38L
• NCBI Official Synonym Symbols: NDR2
• NCBI Protein Information: serine/threonine-protein kinase 38-like
• UniProt Protein Name: Serine/threonine-protein kinase 38-like
• Protein Family: Serine/threonine-protein kinase
• UniProt Gene Name: STK38L
• UniProt Entry Name: ST38L_HUMAN

Uniprot Description

NDR2: a non-receptor S/T kinase of the AGC group. Activated by binding of S100B which releases autoinhibitory N-lobe interactions, enabling ATP to bind followed by autophosphorylation of a serine in the kinase domain. A threonine in the C-terminal domain then undergoes calcium-dependent phosphorylation by an upstream kinase. Interactions between the phosphorylated threonine and the N-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of MOB1/MOBKL1A and MOB2/HCCA2 to the N-terminal of STK38L. May be involved in the regulation of structural processes in neuronal cells.

Protein type: EC 2.7.11.1; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; AGC group; NDR family

Chromosomal Location of Human Ortholog: 12p11.23

Cellular Component: actin cytoskeleton; cytoplasm; membrane

Molecular Function: actin binding; ATP binding; magnesium ion binding; protein binding; protein serine/threonine kinase activity

Biological Process: peptidyl-serine phosphorylation; protein amino acid phosphorylation; regulation of cellular component organization and biogenesis