Rabbit STAT5 Polyclonal Antibody | anti-STAT5 antibody
Phospho-STAT5 antibody
Applications
Immunofluorescence, Western Blot
Purity
Phospho-STAT5 antibody was purified by affinity chromatography
Synonyms
STAT5; Polyclonal Antibody; Phospho-STAT5 antibody; Polyclonal Phospho-STAT5; anti-Phospho-STAT5; Phospho-STAT-5; Phospho-STAT 5; Phospho-STAT5; Signal transducer and activator of transcription 5; STAT-5; anti-STAT5 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Phospho-STAT5 antibody was purified by affinity chromatography
Form/Format
Supplied in PBS buffer containing 50% glycerol, 1% BSA, and 0.02% sodium azide
Concentration
500 ug/ml (varies by lot)
Sequence Length
780
Applicable Applications for anti-STAT5 antibody
Immunofluorescence (IF), Western Blot (WB)
Application Notes
IF: 10-20 ug/ml
WB: 1-4 ug/ml
WB: 1-4 ug/ml
Biological Significance
Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-alpha and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3beta appears to be activated by both while Stat3alpha is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
Phospho-STAT5 antibody was raised in Rabbit using synthetic phospho-peptide corresponding to resides surrounding Tyr694 of mouse Stat5 as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-STAT5 antibody
Rabbit polyclonal Phospho-STAT5 antibody
Product Categories/Family for anti-STAT5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
STAT5
NCBI Official Symbol
stat5a
NCBI Protein Information
STAT5
Research Articles on STAT5
Similar Products
Product Notes
The STAT5 (Catalog #AAA837452) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's STAT5 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Western Blot (WB). IF: 10-20 ug/ml WB: 1-4 ug/ml. Researchers should empirically determine the suitability of the STAT5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STAT5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
