Western Blot (WB)
(Host: RabbitTarget Name: ST8SIA1Sample Tissue: Human U937 Whole Cell lysatesAntibody Dilution: 1ug/ml)
Rabbit anti-Human ST8SIA1 Polyclonal Antibody | anti-ST8SIA1 antibody
ST8SIA1 Antibody - middle region
Western Blot (WB)
(Host: RabbitTarget Name: ST8SIA1Sample Tissue: Human U937 Whole Cell lysatesAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: ST8SIA1Sample Tissue: Human U937 Whole Cell lysatesAntibody Dilution: 1ug/ml)
NCBI and Uniprot Product Information
NCBI Description
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]
Uniprot Description
ST8SIA1: Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. Belongs to the glycosyltransferase 29 family.
Protein type: Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Membrane protein, integral; EC 2.4.99.8
Chromosomal Location of Human Ortholog: 12p12.1-p11.2
Cellular Component: Golgi membrane; integral to membrane; integral to Golgi membrane
Molecular Function: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialyltransferase activity
Biological Process: cellular protein metabolic process; glycosphingolipid biosynthetic process; dolichol-linked oligosaccharide biosynthetic process; positive regulation of cell proliferation; carbohydrate metabolic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
Research Articles on ST8SIA1
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Product Notes
The ST8SIA1 st8sia1 (Catalog #AAA3221946) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ST8SIA1 Antibody - middle region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ST8SIA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ST8SIA1 st8sia1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: RKQMEDCCDP AHLFAMTKMN SPMGKSMWYD GEFLYSFTID NSTYSLFPQA. It is sometimes possible for the material contained within the vial of "ST8SIA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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