Testing Data
(Sample(30 ug of whole cell lysate)A: HeLa S3 12% SDS PAGEPrimary antibody diluted at 1: 500)
Rabbit anti-Human ST3GAL1 Polyclonal Antibody | anti-ST3GAL1 antibody
ST3GAL1 antibody
Immunohistochemistry: 1:100-1:250
Immunofluorescence: 1:100-1:200
Testing Data
(Sample(30 ug of whole cell lysate)A: HeLa S3 12% SDS PAGEPrimary antibody diluted at 1: 500)
Testing Data
(Sample(30 ug of whole cell lysate)A: HeLa S3 12% SDS PAGEPrimary antibody diluted at 1: 500)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded serous OVCA, using ST3GAL1 antibody at 1: 100 dilution.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded serous OVCA, using ST3GAL1 antibody at 1: 100 dilution.)
Immunofluorescence (IF)
(Immunofluorescence analysis of methanol-fixed Hep3B, using SIAT4A antibody at 1: 500 dilution.)
Immunofluorescence (IF)
(Immunofluorescence analysis of methanol-fixed Hep3B, using SIAT4A antibody at 1: 500 dilution.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]
Uniprot Description
ST3GAL1: It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O- linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. Belongs to the glycosyltransferase 29 family.
Protein type: Transferase; Glycan Metabolism - keratan sulfate biosynthesis; EC 2.4.99.4; Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Glycan Metabolism - O-glycan biosynthesis; Glycan Metabolism - glycosphingolipid biosynthesis - globo series
Chromosomal Location of Human Ortholog: 8q24.22
Cellular Component: Golgi membrane; membrane; integral to Golgi membrane
Molecular Function: beta-galactoside alpha-2,3-sialyltransferase activity
Biological Process: keratan sulfate metabolic process; protein amino acid O-linked glycosylation; dolichol-linked oligosaccharide biosynthetic process; O-glycan processing; glycosaminoglycan metabolic process; protein amino acid N-linked glycosylation; protein modification process; pathogenesis; post-translational protein modification; protein amino acid phosphorylation; cellular protein metabolic process; carbohydrate metabolic process; keratan sulfate biosynthetic process; protein amino acid N-linked glycosylation via asparagine; N-acetylneuraminate metabolic process
Research Articles on ST3GAL1
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Product Notes
The ST3GAL1 st3gal1 (Catalog #AAA9409489) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ST3GAL1 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ST3GAL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:250 Immunofluorescence: 1:100-1:200. Researchers should empirically determine the suitability of the ST3GAL1 st3gal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ST3GAL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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