Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SSRP1 antibody.)
Rabbit SSRP1 Polyclonal Antibody | anti-SSRP1 antibody
SSRP1 Polyclonal Antibody
Gene Names
Ssrp; Cf5; CG4817; DmelCG4817; dSsrp; dSSRP; DssRP; dSSRP1; ssrp; SSRP; SSRP1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purification
Synonyms
SSRP1; Polyclonal Antibody; SSRP1 Polyclonal Antibody; FACT; T160; FACT80; anti-SSRP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Sequence Length
723
Applicable Applications for anti-SSRP1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000, IHC: 1:50-1:200
Immunogen
Recombinant protein of human SSRP1
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5911 / sc-5909 / sc-25382
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SSRP1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SSRP1 antibody.)
Related Product Information for anti-SSRP1 antibody
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Calculated MW: 81kDa
NCBI Official Full Name
SSRP1
NCBI Official Synonym Full Names
Structure specific recognition protein
NCBI Official Symbol
Ssrp
NCBI Official Synonym Symbols
Cf5; CG4817; DmelCG4817; dSsrp; dSSRP; DssRP; dSSRP1; ssrp; SSRP; SSRP1
NCBI Protein Information
CG4817 gene product from transcript CG4817-RA
UniProt Protein Name
FACT complex subunit Ssrp1
UniProt Gene Name
Ssrp
UniProt Synonym Gene Names
CF5; SSRP1
UniProt Entry Name
SSRP1_DROME
Uniprot Description
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to single-stranded DNA and RNA with highest affinity for nucleotides G and U. The FACT complex is required for expression of Hox genes.
Research Articles on SSRP1
Similar Products
Product Notes
The SSRP1 ssrp (Catalog #AAA2535320) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SSRP1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SSRP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000, IHC: 1:50-1:200. Researchers should empirically determine the suitability of the SSRP1 ssrp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SSRP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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