Testing Data
(S6580-50 (0.5ug/ml) staining of human kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat anti-Human SRX1 Polyclonal Antibody | anti-SRX1 antibody
SRX1 (Sulfiredoxin 1, Sulfiredoxin-1, C20orf139, SRX) (Biotin)
Gene Names
SRXN1; SRX; Npn3; SRX1; C20orf139
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified by Immunoaffinity chromatography.
Synonyms
SRX1; Polyclonal Antibody; SRX1 (Sulfiredoxin 1; Sulfiredoxin-1; C20orf139; SRX) (Biotin); anti-SRX1 antibody
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human SRX1.
Purity/Purification
Purified by Immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-SRX1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide corresponding to C-KVQSLVDTIREDPD at the internal region of human SRX1 (NP_542763.1). Species sequence homology: bovine, mouse, porcine and rat
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Testing Data
(S6580-50 (0.5ug/ml) staining of human kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Testing Data
(S6580-50 (0.5ug/ml) staining of human kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-SRX1 antibody
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
Product Categories/Family for anti-SRX1 antibody
References
1. Jönsson TJ, Johnson LC, Lowther WT. Structure of the sulphiredoxin-peroxiredoxin complex reveals an essential repair embrace. Nature. 2008 Jan 3;451(7174):98-101.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,259 Da
NCBI Official Full Name
sulfiredoxin-1
NCBI Official Synonym Full Names
sulfiredoxin 1
NCBI Official Symbol
SRXN1
NCBI Official Synonym Symbols
SRX; Npn3; SRX1; C20orf139
NCBI Protein Information
sulfiredoxin-1
UniProt Protein Name
Sulfiredoxin-1
Protein Family
UniProt Gene Name
SRXN1
UniProt Synonym Gene Names
C20orf139; SRX; SRX1
Uniprot Description
SRXN1: Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. Belongs to the sulfiredoxin family.
Protein type: EC 1.8.98.2; Oxidoreductase
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: cytosol
Molecular Function: ATP binding; oxidoreductase activity, acting on a sulfur group of donors; sulfiredoxin activity
Biological Process: response to oxidative stress
Research Articles on SRX1
Similar Products
Product Notes
The SRX1 srxn1 (Catalog #AAA6500766) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The SRX1 (Sulfiredoxin 1, Sulfiredoxin-1, C20orf139, SRX) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SRX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SRX1 srxn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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