Rabbit anti-Human SRPRB Polyclonal Antibody | anti-SRPRB antibody
SRPRB, CT (SRPRB, Signal recognition particle receptor subunit beta, Protein APMCF1)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane. [provided by RefSeq, Jul 2008]
Uniprot Description
SRPRB: Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR. Belongs to the SRP receptor beta subunit family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q22.1
Cellular Component: endoplasmic reticulum membrane; membrane; cytoplasmic microtubule; cytoplasm; integral to membrane
Molecular Function: GTP binding
Biological Process: SRP-dependent cotranslational protein targeting to membrane; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; translation; unfolded protein response; small GTPase mediated signal transduction; gene expression
Research Articles on SRPRB
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Product Notes
The SRPRB srprb (Catalog #AAA644114) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRPRB, CT (SRPRB, Signal recognition particle receptor subunit beta, Protein APMCF1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SRPRB can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the SRPRB srprb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRPRB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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