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Western Blot (WB) (Western blot analysis of SPTA1 expression in K562 cell lysate.)

Rabbit anti-Human SPTA1 Polyclonal Antibody | anti-SPTA1 antibody

Anti-SPTA1 Rabbit pAb

Gene Names
SPTA1; EL2; HPP; HS3; SPH3; SPTA
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
SPTA1; Polyclonal Antibody; Anti-SPTA1 Rabbit pAb; EL2; Elliptocytosis2; erythrocyte; Erythroid alpha spectrin; HS3; SPH3; SPTA; anti-SPTA1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
SPTA1 Antibody detects endogenous levels of total SPTA1
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
2419
Applicable Applications for anti-SPTA1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
A synthesized peptide derived from human SPTA1
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of SPTA1 expression in K562 cell lysate.)

Western Blot (WB) (Western blot analysis of SPTA1 expression in K562 cell lysate.)
Related Product Information for anti-SPTA1 antibody
Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
280kDa
NCBI Official Full Name
spectrin alpha chain, erythrocytic 1
NCBI Official Synonym Full Names
spectrin alpha, erythrocytic 1
NCBI Official Symbol
SPTA1
NCBI Official Synonym Symbols
EL2; HPP; HS3; SPH3; SPTA
NCBI Protein Information
spectrin alpha chain, erythrocytic 1
UniProt Protein Name
Spectrin alpha chain, erythrocytic 1
Protein Family
UniProt Gene Name
SPTA1
UniProt Synonym Gene Names
SPTA

NCBI Description

This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3. [provided by RefSeq, Aug 2017]

Uniprot Description

Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.

Research Articles on SPTA1

Similar Products

Product Notes

The SPTA1 spta1 (Catalog #AAA4751317) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SPTA1 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPTA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the SPTA1 spta1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPTA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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