Western Blot (WB)
(SPRR1A Antibody (C-term) western blot analysis in Jurkat,MCF-7 cell line lysates (35ug/lane).This demonstrates the SPRR1A antibody detected the SPRR1A protein (arrow).)
Rabbit anti-Human SPRR1A Polyclonal Antibody | anti-SPRR1A antibody
SPRR1A Antibody (C-term)
Gene Names
SPRR1A; SPRK
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SPRR1A; Polyclonal Antibody; SPRR1A Antibody (C-term); Cornifin-A; 19 kDa pancornulin; SPRK; Small proline-rich protein IA; SPR-IA; anti-SPRR1A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SPRR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-89 amino acids from the C-terminal region of human SPRR1A.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
61-89
Sequence Length
89
Applicable Applications for anti-SPRR1A antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(SPRR1A Antibody (C-term) western blot analysis in Jurkat,MCF-7 cell line lysates (35ug/lane).This demonstrates the SPRR1A antibody detected the SPRR1A protein (arrow).)
Western Blot (WB)
(SPRR1A Antibody (C-term) western blot analysis in Jurkat,MCF-7 cell line lysates (35ug/lane).This demonstrates the SPRR1A antibody detected the SPRR1A protein (arrow).)
Related Product Information for anti-SPRR1A antibody
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
Product Categories/Family for anti-SPRR1A antibody
References
Jarzab, J., et al. Int. Arch. Allergy Immunol. 151(1):28-37(2010)
?Stemmler, S., et al. Int. J. Immunogenet. 36(4):217-222(2009)
?Kainu, K., et al. Exp. Dermatol. 18(2):109-115(2009)
?Bonilla, I.E., et al. J. Neurosci. 22(4):1303-1315(2002)
?Stemmler, S., et al. Int. J. Immunogenet. 36(4):217-222(2009)
?Kainu, K., et al. Exp. Dermatol. 18(2):109-115(2009)
?Bonilla, I.E., et al. J. Neurosci. 22(4):1303-1315(2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
9877
NCBI Official Full Name
cornifin-A
NCBI Official Synonym Full Names
small proline-rich protein 1A
NCBI Official Symbol
SPRR1A
NCBI Official Synonym Symbols
SPRK
NCBI Protein Information
cornifin-A
UniProt Protein Name
Cornifin-A
Protein Family
UniProt Gene Name
SPRR1A
UniProt Synonym Gene Names
SPR-IA
UniProt Entry Name
SPR1A_HUMAN
Uniprot Description
SPRR1A: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Belongs to the cornifin (SPRR) family.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 1q21-q22
Cellular Component: cytoplasm; cornified envelope
Molecular Function: protein binding, bridging; protein binding; structural molecule activity
Biological Process: keratinocyte differentiation; epidermis development; keratinization; peptide cross-linking
Research Articles on SPRR1A
Similar Products
Product Notes
The SPRR1A sprr1a (Catalog #AAA9210906) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 61-89. The SPRR1A Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPRR1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SPRR1A sprr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPRR1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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