Western Blot (WB)
(SPOCK3 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SPOCK3 antibody detected the SPOCK3 protein (arrow).)
Rabbit SPOCK3 Polyclonal Antibody | anti-SPOCK3 antibody
SPOCK3 Antibody (N-term)
Western Blot (WB)
(SPOCK3 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SPOCK3 antibody detected the SPOCK3 protein (arrow).)
Western Blot (WB)
(SPOCK3 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SPOCK3 antibody detected the SPOCK3 protein (arrow).)
covalently linked glycosaminoglycans, are components of the
extracellular matrix. SPOCK3 encodes a member of a novel
Ca(2+)-binding proteoglycan family.
Kamioka, M., et al. Leuk. Res. 33(7):913-918(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Nakada, M., et al. Cancer Res. 61(24):8896-8902(2001)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
SPOCK3: May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 4q32.3
Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space
Molecular Function: metalloendopeptidase inhibitor activity; glycosaminoglycan binding; calcium ion binding
Biological Process: signal transduction; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
Research Articles on SPOCK3
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Product Notes
The SPOCK3 spock3 (Catalog #AAA9202175) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 36-63. The SPOCK3 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's SPOCK3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SPOCK3 spock3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPOCK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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