Western Blot (WB)
(SPINT1 Antibody (Center) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the SPINT1 antibody detected the SPINT1 protein (arrow).)
Rabbit anti-Human SPINT1 Polyclonal Antibody | anti-SPINT1 antibody
SPINT1 Antibody (Center)
Gene Names
SPINT1; HAI; HAI1; MANSC2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SPINT1; Polyclonal Antibody; SPINT1 Antibody (Center); Kunitz-type protease inhibitor 1; Hepatocyte growth factor activator inhibitor type 1; HAI-1; HAI1; anti-SPINT1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SPINT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the Central region of human SPINT1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
178-207
Sequence Length
513
Applicable Applications for anti-SPINT1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(SPINT1 Antibody (Center) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the SPINT1 antibody detected the SPINT1 protein (arrow).)
Western Blot (WB)
(SPINT1 Antibody (Center) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the SPINT1 antibody detected the SPINT1 protein (arrow).)
Related Product Information for anti-SPINT1 antibody
The protein encoded by this gene is a member of the Kunitz
family of serine protease inhibitors. The protein is a potent
inhibitor specific for HGF activator and is thought to be involved
in the regulation of the proteolytic activation of HGF in injured
tissues. Alternative splicing results in multiple variants encoding
different isoforms.
family of serine protease inhibitors. The protein is a potent
inhibitor specific for HGF activator and is thought to be involved
in the regulation of the proteolytic activation of HGF in injured
tissues. Alternative splicing results in multiple variants encoding
different isoforms.
Product Categories/Family for anti-SPINT1 antibody
References
Chen, Y.W., et al. J. Biol. Chem. 285(41):31755-31762(2010)
Kauppinen, J.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(9):2133-2142(2010)
Nakamura, K., et al. Int. J. Oncol. 35(2):239-248(2009)
Wang, J.K., et al. Am. J. Physiol., Cell Physiol. 297 (2), C459-C470 (2009) :
Cheng, H., et al. Cancer Res. 69(5):1828-1835(2009)
Kauppinen, J.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(9):2133-2142(2010)
Nakamura, K., et al. Int. J. Oncol. 35(2):239-248(2009)
Wang, J.K., et al. Am. J. Physiol., Cell Physiol. 297 (2), C459-C470 (2009) :
Cheng, H., et al. Cancer Res. 69(5):1828-1835(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58398
NCBI Official Full Name
kunitz-type protease inhibitor 1 isoform 2
NCBI Official Synonym Full Names
serine peptidase inhibitor, Kunitz type 1
NCBI Official Symbol
SPINT1
NCBI Official Synonym Symbols
HAI; HAI1; MANSC2
NCBI Protein Information
kunitz-type protease inhibitor 1
UniProt Protein Name
Kunitz-type protease inhibitor 1
Protein Family
UniProt Gene Name
SPINT1
UniProt Synonym Gene Names
HAI1; HAI-1
UniProt Entry Name
SPIT1_HUMAN
NCBI Description
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Uniprot Description
SPINT1: Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14). 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 15q15.1
Cellular Component: extracellular space; membrane; extracellular region
Molecular Function: serine-type endopeptidase inhibitor activity
Biological Process: extracellular matrix organization and biogenesis
Research Articles on SPINT1
Similar Products
Product Notes
The SPINT1 spint1 (Catalog #AAA9213328) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 178-207. The SPINT1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPINT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SPINT1 spint1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPINT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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