Western Blot (WB)
(Western blotAll lanes: SPIN1 antibody at 1.45ug/mlLane 1:Hela whole cell lysateLane 2:293T whole cell lysateLane 3:HepG2 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 30kDaObserved band size: 30kDa)
Rabbit anti-Human SPIN1 Polyclonal Antibody | anti-SPIN1 antibody
SPIN1 Antibody
Gene Names
SPIN1; SPIN; TDRD24
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
SPIN1; Polyclonal Antibody; SPIN1 Antibody; Spindlin-1; Ovarian cancer-related protein; Spindlin1; OCR; SPIN; anti-SPIN1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
262
Applicable Applications for anti-SPIN1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Spindlin-1 protein (1-262AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160836
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Western Blot (WB)
(Western blotAll lanes: SPIN1 antibody at 1.45ug/mlLane 1:Hela whole cell lysateLane 2:293T whole cell lysateLane 3:HepG2 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 30kDaObserved band size: 30kDa)
Western Blot (WB)
(Western blotAll lanes: SPIN1 antibody at 1.45ug/mlLane 1:Hela whole cell lysateLane 2:293T whole cell lysateLane 3:HepG2 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 30kDaObserved band size: 30kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7046657 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7046657 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis using MBS7046657 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis using MBS7046657 at dilution 1:100)
Related Product Information for anti-SPIN1 antibody
Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,601 Da
NCBI Official Full Name
spindlin-1
NCBI Official Synonym Full Names
spindlin 1
NCBI Official Symbol
SPIN1
NCBI Official Synonym Symbols
SPIN; TDRD24
NCBI Protein Information
spindlin-1
UniProt Protein Name
Spindlin-1
Protein Family
UniProt Gene Name
SPIN1
UniProt Synonym Gene Names
OCR; SPIN
UniProt Entry Name
SPIN1_HUMAN
Uniprot Description
SPIN1: May play a role in cell-cycle regulation during the transition from gamete to embryo. Belongs to the SPIN/STSY family.
Protein type: DNA-binding; Nucleolus
Chromosomal Location of Human Ortholog: 9q22.1
Cellular Component: nucleolus; nucleus
Molecular Function: methylated histone residue binding; protein binding
Biological Process: positive regulation of Wnt receptor signaling pathway; rRNA transcription
Research Articles on SPIN1
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Product Notes
The SPIN1 spin1 (Catalog #AAA7046657) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPIN1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPIN1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the SPIN1 spin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPIN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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