Rabbit speB Polyclonal Antibody | anti-speB antibody
speB Antibody, FITC conjugated
Reactivity
Streptococcus pyogenes serotype M28
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
speB; Polyclonal Antibody; speB Antibody; FITC conjugated; Streptopain; Exotoxin type B; SPE B; Streptococcal cysteine proteinase; Streptococcus peptidase A; SPP; M28_Spy1721; anti-speB antibody
Host
Rabbit
Reactivity
Streptococcus pyogenes serotype M28
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid;
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Sequence Length
398
Applicable Applications for anti-speB antibody
ELISA (EIA)
Immunogen
Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)
Species
Streptococcus pyogenes serotype M28 (strain MGAS6180)
Research Area
Others
Relevance
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).
Conjugation
FITC
Preparation and Storage
Upon receipt store at -20°C or -80°C. Avoid repeated freeze.
Related Product Information for anti-speB antibody
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
streptopain
UniProt Protein Name
Streptopain
Protein Family
UniProt Gene Name
speB
UniProt Synonym Gene Names
SPP
UniProt Entry Name
SPEB_STRPM
Uniprot Description
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing ().
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Product Notes
The speB speb (Catalog #AAA7050359) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The speB Antibody, FITC conjugated reacts with Streptococcus pyogenes serotype M28 and may cross-react with other species as described in the data sheet. AAA Biotech's speB can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the speB speb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "speB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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