Western Blot (WB)
(Anti- SP2 Picoband antibody, MBS178095, Western blottingAll lanes: Anti SP2 (MBS178095) at 0.5ug/mlLane 1: Rat Lung Tissue Lysate at 50ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugPredicted bind size: 72KDObserved bind size: 72KD )
anti-Human, Rat SP2 Polyclonal Antibody | anti-SP2 antibody
Anti-SP2 Antibody
Western Blot (WB)
(Anti- SP2 Picoband antibody, MBS178095, Western blottingAll lanes: Anti SP2 (MBS178095) at 0.5ug/mlLane 1: Rat Lung Tissue Lysate at 50ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugPredicted bind size: 72KDObserved bind size: 72KD )
Western Blot (WB)
(Anti- SP2 Picoband antibody, MBS178095, Western blottingAll lanes: Anti SP2 (MBS178095) at 0.5ug/mlLane 1: Rat Lung Tissue Lysate at 50ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugPredicted bind size: 72KDObserved bind size: 72KD )
Background: Transcription factor Sp2 is a protein that in humans is encoded by the SP2 gene. This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008]
Uniprot Description
SP2: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Belongs to the Sp1 C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; DNA-binding; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 17q21.32
Cellular Component: nucleus
Molecular Function: DNA binding; histone deacetylase binding; metal ion binding; protein binding
Biological Process: immune response; multicellular organism growth; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
Research Articles on SP2
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Product Notes
The SP2 sp2 (Catalog #AAA178095) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-SP2 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot Concentration: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the SP2 sp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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