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Western Blot (Western Blot analysis using SP1 antibodySP1 antibody used at 0.2-1 ug/ml to detect target protein.)

Rabbit SP1 Polyclonal Antibody | anti-SP1 antibody

SP1 antibody

Gene Names
Sp1; Sp1-1; AA450830; AI845540; 1110003E12Rik
Applications
Western Blot
Synonyms
SP1; Polyclonal Antibody; SP1 antibody; Polyclonal SP1; Anti-SP1; SP 1; SP-1; anti-SP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Lyophilized powder. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (varies by lot)
Sequence Length
101
Applicable Applications for anti-SP1 antibody
Western Blot (WB)
Application Notes
WB: 2.5 ug/ml
Biological Significance
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses.
Cross-Reactivity
Mouse, Rat, Pig
Immunogen
SP1 antibody was raised in rabbit using the C terminal of SP1 as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.

Western Blot

(Western Blot analysis using SP1 antibodySP1 antibody used at 0.2-1 ug/ml to detect target protein.)

Western Blot (Western Blot analysis using SP1 antibodySP1 antibody used at 0.2-1 ug/ml to detect target protein.)
Related Product Information for anti-SP1 antibody
Rabbit polyclonal SP1 antibody
Product Categories/Family for anti-SP1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Sp1, partial
NCBI Official Synonym Full Names
trans-acting transcription factor 1
NCBI Official Symbol
Sp1
NCBI Official Synonym Symbols
Sp1-1; AA450830; AI845540; 1110003E12Rik
NCBI Protein Information
transcription factor Sp1

Uniprot Description

SP1: a transcription factor of the Sp1 C2H2-type zinc-finger protein family. Phosphorylated and activated by MAPK. Dephosphorylation by PTEN inhibits DNA binding. Binds to p38 in the nucleus. Interacts with Huntingtin and TAFII130. Transcriptional activity of SP1 and TAFII130 disrupted in early Huntingtin's Disease.

Protein type: Transcription factor; DNA-binding; C2H2-type zinc finger protein

Cellular Component: nucleoplasm; cytoplasm; nuclear chromatin; nucleus

Molecular Function: protein C-terminus binding; histone acetyltransferase binding; protein binding; protein homodimerization activity; nucleic acid binding; DNA binding; sequence-specific DNA binding; metal ion binding; histone deacetylase binding; double-stranded DNA binding; bHLH transcription factor binding; transcription factor activity; transcription factor binding

Biological Process: transcription from RNA polymerase II promoter; embryonic placenta development; ossification; transcription, DNA-dependent; megakaryocyte differentiation; in utero embryonic development; embryonic skeletal development; positive regulation of transcription, DNA-dependent; embryonic process involved in female pregnancy; rhythmic process; enucleate erythrocyte differentiation; liver development; trophectodermal cell differentiation; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; embryonic camera-type eye morphogenesis; lung development

Research Articles on SP1

Similar Products

Product Notes

The SP1 (Catalog #AAA832943) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 2.5 ug/ml. Researchers should empirically determine the suitability of the SP1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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