Rabbit anti-Human SOX15 Polyclonal Antibody | anti-SOX15 antibody
SOX15 Antibody
Gene Names
SOX15; SOX20; SOX26; SOX27
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
SOX15; Polyclonal Antibody; SOX15 Antibody; Protein SOX-12; Protein SOX-15; Protein SOX-20; SOX 12 protein; SOX 15; SOX 15 protein; SOX 20 protein; SOX12; SOX12 protein; SOX15 protein; SOX15_HUMAN; SOX20; SOX20 protein; SOX26; SOX27; SRY box 15; SRY sex determining region Y box 15; SRY sex determining region Y box 20; SRYbox 15; anti-SOX15 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
SOX15 Antibody detects endogenous levels of total SOX15.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-SOX15 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Subunit Structure
Interacts with HAND1; the interaction enhances HAND1-induced differentiation of trophoblast giant cells (By similarity). Interacts with POU5F1 (OCT3/4); binds synergistically with POU5F1 to DNA (By similarity). Interacts with FHL3; the interaction recruits the transcriptional coactivator FHL3 to the FOXK1 promoter (By similarity).
Tissue Specificity
Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.
Function
Transcription factor that binds to DNA at the 5'-AACAATG-3' consensus sequence (By similarity). Acts as a transcriptional activator and repressor (By similarity). Binds synergistically with POU5F1 (OCT3/4) to gene promoters (By similarity). Binds to the FOXK1 promoter and recruits FHL3, resulting in transcriptional activation of FOXK1 which leads to myoblast proliferation (By similarity). Acts as an inhibitor of myoblast differentiation via transcriptional repression which leads to down-regulation of the muscle-specific genes MYOD and MYOG (By similarity). Involved in trophoblast giant cell differentiation via enhancement of HAND1 transcriptional activity (By similarity). Regulates transcription of HRC via binding to it proximal enhancer region (By similarity). Involved in skeletal muscle regeneration (By similarity). Also plays a role in the development of myogenic precursor cells (By similarity).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,393 Da
NCBI Official Full Name
protein SOX-15
NCBI Official Synonym Full Names
SRY-box 15
NCBI Official Symbol
SOX15
NCBI Official Synonym Symbols
SOX20; SOX26; SOX27
NCBI Protein Information
protein SOX-15
UniProt Protein Name
Protein SOX-15
Protein Family
UniProt Gene Name
SOX15
UniProt Synonym Gene Names
SOX12; SOX20; SOX26; SOX27
UniProt Entry Name
SOX15_HUMAN
NCBI Description
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008]
Research Articles on SOX15
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Product Notes
The SOX15 sox15 (Catalog #AAA9629306) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SOX15 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SOX15 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the SOX15 sox15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOX15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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